What should I Know Regarding Pregnancy, Nursing and Administering Qudexy XR to Children or the Elderly?

If you are pregnant

  • Not Recommended:
  • If you are nursing

  • If you are an adult over 60

  • management or monitoring precaution: Renal-Decrease dose for CrCl < 70 mL/min. to minimize CNS toxicities. Neuro/Psych-Can cause cognitive impairment, ataxia, impaired psychomotor function, syncope, and increase risk for additional falls in those predisposed. Vision-Visual field defects have been reported in patients receiving topiramate independent of elevated intraocular pressure. In clinical trials, most of these events were reversible after topiramate discontinuation.
  • Pediatric use

  • Severe Precaution: Risk of acidosis, hyperammonemia, oligohidrosis, osteomalacia, and rare angle closure glaucoma. Monitor serum bicarbonate, signs of encephalopathy (ammonia level), changes in cognition, behavior and vision, and check growth rate.
  • Severe Precaution: Risk of metabolic acidosis, slowed growth, infection, hyperthermia, oligohidrosis, increased creatinine, hyperammonemia, osteomalacia, secondary angle closure glaucoma. Efficacy not demonstrated age <2 years.
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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.