ZYDELIG Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • low amount of sodium in the blood
  • anemia
  • low levels of a type of white blood cell called neutrophils
  • a decreased number of lymphocytes in the blood
  • pneumonia
  • inflammation of the large intestine
  • inflammation of the liver called hepatitis
  • excessive diarrhea
  • abnormal liver function tests
  • a high alanine transaminase level
  • a high aspartate transaminase level
  • If experienced, these tend to have a Less Severe expression i

  • fever
  • low energy
  • chills
  • a skin rash
  • cough
  • nausea
  • vomiting
  • intense abdominal pain
  • INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

  • low blood sugar
  • decreased blood platelets
  • a type of inflammation of the lung called interstitial pneumonitis
  • skin rash with sloughing
  • a type of bumpy skin rash called a maculopapular rash
  • sepsis
  • If experienced, these tend to have a Less Severe expression i

  • a common cold
  • stuffy nose
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • gastroesophageal reflux disease
  • urinary tract infection
  • joint pain
  • backache
  • muscle spasm
  • difficulty sleeping
  • pain
  • fluid retention in the legs, feet, arms or hands
  • decreased appetite
  • headache
  • generalized weakness
  • night sweats
  • RARE side effects

    If experienced, these tend to have a Severe expression i

  • an unusual viral infection called cytomegalovirus infection
  • pneumonia with a fungus called Pneumocystis jirovecii
  • a hole in the intestine
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • a significant type of allergic reaction called anaphylaxis
  • a rupture in the wall of the stomach or intestine
  • progressive multifocal leukoencephalopathy, a type of brain infection
  • a type of significant allergic skin reaction called DRESS syndrome
  • If experienced, these tend to have a Less Severe expression i

  • itching
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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.