This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Ledipasvir may increase the amount of rosuvastatin you absorb into your body.
What might happen:
The amount of rosuvastatin in your blood may increase and cause harmful effects.
What you should do about this interaction:
Make sure to let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Let your doctor know if you have any unexplained muscle pain, tenderness, weakness, or discoloration of your urine. Your doctor may want to change your cholesterol medicine.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Crestor (rosuvastatin calcium) US prescribing information. AstraZeneca Pharmaceuticals LP September, 2018.
- 2.Harvoni (ledipasvir and sofosbuvir) prescribing information. Gilead Sciences November, 2017.
- 3.Davis B and Pimentel J. Personal Communications: Harvoni. Gilead Sciences November 14 and 18, 2014.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.