Selected NSAIDs/Selected CYP2C9 Inhibitors Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Some medicines slow down how quickly your liver processes certain non-steroidal anti-inflammatory medicines (NSAIDs).
What might happen:
The amount of the NSAID in your body may increase. This may increase your risk of having side effects from these medicines.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to monitor you more closely or may want to lower the dose of your NSAID while you are taking your other medicine.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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- 4.Arthrotec (diclofenac sodium/misoprostol) US prescribing information. Pfizer, Inc. May, 2016.
- 5.Dynastat (parecoxib) UK summary of product characteristics. Pfizer Limited June 26, 2020.
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- 9.Vfend (voriconazole) US prescribing information. Pfizer Inc. January, 2019.
- 10.Diflucan (fluconazole) US prescribing information. Pfizer Inc. February, 2019.
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- 12.Mobic (meloxicam) US prescribing information. Boehringer Ingelheim May, 2016.
- 13.Feldene (piroxicam) US prescribing information. Pfizer Inc. May, 2019.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.