XIGDUO XR Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • urinary tract infection

If experienced, these tend to have a Less Severe expression i

  • inadequate vitamin B12
  • a common cold
  • taste impairment
  • weight loss
  • headache
  • nausea
  • vomiting
  • gas
  • diarrhea
  • abdominal bloating
  • a yeast infection of the vagina and vulva
  • throat irritation

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • trouble breathing
  • dehydration
  • low blood pressure

If experienced, these tend to have a Less Severe expression i

  • a stuffy and runny nose
  • indigestion
  • constipation
  • a nail disorder
  • dizziness
  • flu-like symptoms
  • excessive sweating
  • chills
  • a skin rash
  • temporary redness of face and neck
  • heart throbbing or pounding
  • high cholesterol
  • high amount of phosphate in the blood
  • orthostatic hypotension, a form of low blood pressure
  • the flu
  • an infection of the genitals or urinary tract
  • itching of the genital area
  • backache
  • nausea
  • difficult or painful urination
  • an increased need to urinate often
  • decreased blood volume
  • Candida infection of the glans penis
  • high levels of hemoglobin

RARE side effects

If experienced, these tend to have a Severe expression i

  • low blood sugar
  • increased blood acidity due to high levels of lactic acid
  • megaloblastic anemia
  • acute respiratory distress syndrome, a type of lung disorder
  • liver damage
  • inflammation of the liver with stoppage of bile flow
  • a systemic inflammatory response called sepsis due to an infection with bacteria
  • cancer of the bladder
  • a complication of diabetes with high blood ketone levels called diabetic ketoacidosis
  • a metabolic condition where the body cannot adequately use sugars called ketoacidosis
  • excess body acid
  • acute kidney failure
  • pyelonephritis, infection and inflammation of the kidney and renal pelvis
  • decreased kidney function
  • a broken bone
  • a type of allergic reaction called angioedema
  • a hypersensitivity reaction to a drug
  • pancreatitis
  • urosepsis, a bacterial infection originating from the urinary tract
  • necrotizing fasciitis, a condition where deep tissues die in the area of the genitals to the anus

If experienced, these tend to have a Less Severe expression i

  • hives

Free RX Coupon

Save up to 80% on your prescriptions.

Available coupons

Save up to 80% on your prescription with WebMDRx

Drug Survey

Are you currently using dapagliflozin-metformin oral?

This survey is being conducted by the WebMD marketing sciences department.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.