Nivolumab Intravenous Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • thyroid gland inflammation
  • low amount of magnesium in the blood
  • high levels of potassium in the blood
  • low amount of potassium in the blood
  • low levels of a type of white blood cell called neutrophils
  • inflammation of the large intestine
  • abnormal liver function tests
  • a high alanine transaminase level
  • a high aspartate transaminase level
  • If experienced, these tend to have a Less Severe expression i

  • constipation
  • itching
  • joint pain
  • backache
  • fever
  • low energy
  • a skin rash
  • fluid retention in the legs, feet, arms or hands
  • decreased appetite
  • headache
  • cough
  • nausea
  • vomiting
  • diarrhea
  • generalized weakness
  • intense abdominal pain
  • pain in the muscles or bones
  • INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

  • a systemic inflammatory response called sepsis due to an infection with bacteria
  • decreased function of the adrenal gland
  • demyelinating disorder
  • a clot in the lung
  • pneumonia
  • escape of fluid into the lungs
  • a type of inflammation of the lung called interstitial pneumonitis
  • lung failure causing loss of breath
  • an abnormal connection between the esophagus and windpipe
  • liver inflammation resulting from an abnormal immune response
  • bleeding of the stomach or intestines
  • decreased kidney function
  • high amount of bilirubin in the blood
  • a hypersensitivity reaction to a drug
  • lung tissue problem
  • If experienced, these tend to have a Less Severe expression i

  • dry eye
  • bronchitis
  • muscle weakness
  • dizziness
  • chills
  • visible water retention
  • temporary redness of face and neck
  • weight loss
  • difficulty swallowing
  • fast heartbeat
  • peripheral sensory nerve disorder
  • RARE side effects

    If experienced, these tend to have a Severe expression i

  • an unusual viral infection called cytomegalovirus infection
  • sarcoidosis
  • a complication of diabetes with high blood ketone levels called diabetic ketoacidosis
  • diabetes
  • pituitary hormone deficiency
  • acidosis, a high level of acid in the blood
  • destruction of red blood cells by body's own antibodies
  • low blood counts due to bone marrow failure
  • anemia
  • increased eosinophils in the blood
  • encephalitis
  • Guillain-Barre syndrome
  • progressive muscle weakness with carcinoma
  • a disease with shrinking and weaker muscles called myopathy
  • inflammation of the uvea of the eye
  • inflammation of the iris and ciliary body of the eye
  • high blood pressure
  • inflammation of the covering of the heart or pericardium
  • atrial fibrillation
  • ventricular arrhythmias, a type of abnormal heart rhythm
  • inflammation of the middle tissue heart muscle
  • inflammation of the blood vessels
  • an ulcer of the duodenum
  • inflammation of the liver called hepatitis
  • a type of kidney inflammation called interstitial nephritis
  • kidney failure
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • skin rash with sloughing
  • muscle pain and stiffness in the shoulder, neck and pelvis
  • a condition with muscle tissue breakdown called rhabdomyolysis
  • muscle inflammation
  • erythrodysesthesia or tingling, pain, redness, and edema in the hands and feet
  • graft-versus-host disease
  • inflammation of the duodenum
  • a condition with dry eyes, dry mouth and arthritis called Sjogren's syndrome
  • a rupture in the wall of the stomach or intestine
  • bleeding from the lungs
  • pancreatitis
  • a facial nerve disorder
  • osteoarthritis of the spine
  • inflammation of the pituitary gland
  • sepsis
  • cytokine release syndrome, a sudden activation of the immune system
  • histiocytic necrotizing lymphadenitis, a condition with swollen glands in the neck and flu symptoms
  • hemophagocytic lymphohistiocytosis, a condition where the body makes too many activated immune cells
  • Vogt-Koyanagi-Harada disease, an inflammatory disease of certain cells of the eyes, ears and skin
  • tumor lysis syndrome
  • If experienced, these tend to have a Less Severe expression i

  • dehydration
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • a type of stomach irritation called gastritis
  • kidney inflammation
  • arthritis
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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.