Opdivo Vial Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • Abnormal Liver Function Tests
  • Decreased Neutrophils A Type Of White Blood Cell
  • High Alanine Transaminase Level
  • High Amount Of Potassium In The Blood
  • High Aspartate Transaminase Level
  • Inflammation Of The Large Intestine
  • Low Amount Of Magnesium In The Blood
  • Low Amount Of Potassium In The Blood

If experienced, these tend to have a Less Severe expression

  • Acute Infection Of The Nose, Throat Or Sinus
  • Backache
  • Constipation
  • Cough
  • Diarrhea
  • Feel Like Throwing Up
  • Feeling Weak
  • Fever
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • Head Pain
  • High Blood Levels Of The Lipase Enzyme
  • Intense Abdominal Pain
  • Itching
  • Joint Pain
  • Loss Of Appetite
  • Low Amount Of Sodium In The Blood
  • Low Energy
  • Muscle Or Bone Pain
  • Rash
  • Throwing Up
  • Trouble Breathing

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • Demyelinating Disease
  • Escape Of Fluid Into The Lungs
  • High Amount Of Bilirubin In The Blood
  • Hypersensitivity Drug Reaction
  • Inflammation In Lungs Caused By Allergic Reaction
  • Kidney Disease With Reduction In Kidney Function
  • Lung Embolism
  • Lung Failure Causing Loss Of Breath
  • Pneumonia
  • Sepsis Caused By Bacteria

If experienced, these tend to have a Less Severe expression

  • Bronchitis
  • Chills
  • Condition Where Part Of The Skin Loses Pigment
  • Dizzy
  • Dry Eye
  • Fast Heartbeat
  • High Blood Sugar
  • Hypothyroidism
  • Muscle Weakness
  • Overactive Thyroid Gland
  • Peripheral Neuropathy
  • Temporary Redness Of Face And Neck
  • Visible Water Retention
  • Weight Loss

RARE side effects


If experienced, these tend to have a Severe expression

  • A Rupture In The Wall Of The Stomach Or Intestine
  • Acidosis
  • Atrial Fibrillation
  • Decreased Function Of The Adrenal Gland
  • Diabetes
  • Diabetic Ketoacidosis
  • Encephalitis
  • Erythema Multiforme
  • Facial Nerve Disorder
  • Guillain-Barre Syndrome
  • Heart Ventricle Rhythm Problem
  • Hepatitis
  • High Blood Pressure
  • Histiocytic Necrotizing Lymphadenitis
  • Incompatibility Reaction Following Bone Marrow Transplant
  • Increased Eosinophils In The Blood
  • Inflammation Of Duodenum Or Top Portion Of Small Intestine
  • Inflammation Of The Covering Of The Heart Or Pericardium
  • Inflammation Of The Iris And Ciliary Body Of The Eye
  • Inflammation Of The Middle Tissue Heart Muscle
  • Inflammation Of The Pituitary Gland
  • Inflammation Of The Uvea Of The Eye
  • Interstitial Nephritis
  • Joint Damage Of Spine Causing Pain And Loss Of Function
  • Kidney Failure
  • Lung Tissue Problems
  • Muscle Inflammation
  • Muscle Pain And Stiffness In Shoulder, Neck And Pelvis
  • Muscle Problems
  • Pancreatitis
  • Pituitary Hormone Deficiency
  • Progressive Muscle Weakness With Carcinoma
  • Rhabdomyolysis
  • Sarcoidosis
  • Sepsis
  • Sjogren's Syndrome; Causes Dry Eyes & Mouth And Arthritis
  • Skin Rash With Sloughing
  • Stevens-Johnson Syndrome
  • Tingling, Pain, Redness And Edema Of Hands And Feet
  • Toxic Epidermal Necrolysis
  • Ulcer Of The Duodenum
  • Vasculitis
  • Vogt-Koyanagi-Harada Disease

If experienced, these tend to have a Less Severe expression

  • Arthritis
  • Burning Stomach
  • Disorder Of The Peripheral Nerves That Cause Movement
  • Extreme Loss Of Body Water
  • High Blood Levels Of The Amylase Enzyme
  • Kidney Inflammation
  • Painful, Red Or Swollen Mouth
  • Peripheral Nerve Inflammation
  • Psoriasis

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.