Opdivo Vial Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • A High Alanine Transaminase Level
  • A High Aspartate Transaminase Level
  • Abnormal Liver Function Tests
  • High Levels Of Potassium In The Blood
  • Inflammation Of The Large Intestine
  • Low Amount Of Magnesium In The Blood
  • Low Amount Of Potassium In The Blood
  • Low Levels Of A Type Of White Blood Cell Called Neutrophils

If experienced, these tend to have a Less Severe expression

  • A Common Cold
  • A Skin Rash
  • Backache
  • Constipation
  • Cough
  • Decreased Appetite
  • Diarrhea
  • Fever
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • Generalized Weakness
  • Head Pain
  • High Blood Levels Of The Lipase Enzyme
  • Intense Abdominal Pain
  • Itching
  • Joint Pain
  • Low Amount Of Sodium In The Blood
  • Low Energy
  • Nausea
  • Pain In The Muscles Or Bones
  • Trouble Breathing
  • Vomiting

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Clot In The Lung
  • A Systemic Inflammatory Response Called Sepsis Due To An Infection With Bacteria
  • An Allergic Reaction To A Drug
  • Demyelination, A Type Of Nervous System Disorder
  • Escape Of Fluid Into The Lungs
  • High Amount Of Bilirubin In The Blood
  • Inflammation In The Lungs Due To An Allergic Reaction
  • Kidney Disease With Reduction In Kidney Function
  • Lung Failure Causing Loss Of Breath
  • Pneumonia

If experienced, these tend to have a Less Severe expression

  • A Condition Where Portions Of The Skin Lose The Natural Color Called Vitiligo
  • A Condition With Low Thyroid Hormone Levels
  • Bronchitis
  • Chills
  • Dizziness
  • Dry Eye
  • Fast Heartbeat
  • High Blood Sugar
  • Muscle Weakness
  • Overactive Thyroid Gland
  • Peripheral Sensory Nerve Disorder
  • Temporary Redness Of Face And Neck
  • Visible Water Retention
  • Weight Loss

RARE side effects


If experienced, these tend to have a Severe expression

  • A Complication Of Diabetes With High Blood Ketone Levels Called Diabetic Ketoacidosis
  • A Condition With Dry Eyes, Dry Mouth And Arthritis Called Sjogren's Syndrome
  • A Condition With Muscle Tissue Breakdown Called Rhabdomyolysis
  • A Disease With Shrinking And Weaker Muscles Called Myopathy
  • A Facial Nerve Disorder
  • A Rupture In The Wall Of The Stomach Or Intestine
  • A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome
  • A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis
  • A Type Of Kidney Inflammation Called Interstitial Nephritis
  • Acidosis, A High Level Of Acid In The Blood
  • An Ulcer Of The Duodenum
  • An Unusual Viral Infection That Can Affect A Part Of The Body Or Spread Called CMV Disease
  • Atrial Fibrillation
  • Decreased Function Of The Adrenal Gland
  • Diabetes
  • Encephalitis
  • Erythema Multiforme, A Type Of Allergic Skin Reaction
  • Graft Versus Host Disease
  • Guillain-Barre Syndrome
  • High Blood Pressure
  • Histiocytic Necrotizing Lymphadenitis, A Condition With Swollen Glands In The Neck And Flu Symptoms
  • Increased Eosinophils In The Blood
  • Inflammation Of The Blood Vessels
  • Inflammation Of The Covering Of The Heart Or Pericardium
  • Inflammation Of The Duodenum
  • Inflammation Of The Iris And Ciliary Body Of The Eye
  • Inflammation Of The Liver Called Hepatitis
  • Inflammation Of The Middle Tissue Heart Muscle
  • Inflammation Of The Pituitary Gland
  • Inflammation Of The Uvea Of The Eye
  • Kidney Failure
  • Lung Tissue Problems
  • Muscle Inflammation
  • Muscle Pain And Stiffness In The Shoulder, Neck And Pelvis
  • Osteoarthritis Of The Spine
  • Pancreatitis
  • Pituitary Hormone Deficiency
  • Progressive Muscle Weakness With Carcinoma
  • Sarcoidosis
  • Sepsis
  • Skin Rash With Sloughing
  • Tingling, Pain, Redness, And Edema Or The Hands And Feet
  • Ventricular Arrhythmias, A Type Of Abnormal Heart Rhythm
  • Vogt-Koyanagi-Harada Disease, An Inflammatory Disease Of Certain Cells Of The Eyes, Ears And Skin

If experienced, these tend to have a Less Severe expression

  • A Disorder Of The Peripheral Nerves That Enable Movement Called Peripheral Motor Neuropathy
  • A Type Of Stomach Irritation Called Gastritis
  • Arthritis
  • Dehydration
  • High Blood Levels Of The Amylase Enzyme
  • Kidney Inflammation
  • Peripheral Nerve Inflammation
  • Psoriasis
  • Stomatitis, A Condition With Painful Swelling And Sores Inside The Mouth

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.