If you are:
Only When Necessary: NON-TERATOGENIC COMPLICATIONS (RESP, GI,CNS) WITH EXPOSURE DURING 3RD TRIMESTER
Precaution: LIMITED DATA SUGGEST LOW LEVELS EXCRETED RESULTING IN INFANT SEDATION
An adult over 60:
management or monitoring precaution: Neuro/Psych-Higher risk of tardive dyskinesia in the elderly. Anticholinergic effects cause sedation, worsen cognitive impairment and increase fall risk. Increased risk of death in senile dementia. Maximum of 7.5mg/day. Cardiovascular-May cause orthostatic hypotension at higher doses. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Giving Zyprexa to a child under 12:
management or monitoring precaution: Increased risk of sedation, hyperlipidemia and increased prolactin levels. Monitor weight and liver functions tests.
Severe Precaution: Safety and efficacy not established age less than 10 years for combination with fluoxetine.