ONIVYDE Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • significantly decreased activity of the bone marrow
  • anemia
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • a decreased number of lymphocytes in the blood
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • fever
  • visible water retention
  • diarrhea
  • excessive diarrhea

If experienced, these tend to have a Less Severe expression i

  • constipation
  • hair loss
  • dizziness
  • low energy
  • pain
  • a skin rash
  • temporary redness of face and neck
  • decreased appetite
  • weight loss
  • headache
  • cough
  • nausea
  • vomiting
  • stomach cramps
  • generalized weakness

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • a systemic inflammatory response called sepsis due to an infection with bacteria
  • decreased pupil size
  • slow heartbeat
  • low blood pressure
  • pneumonia
  • inflammation of the lining of the stomach and intestines
  • acute kidney failure
  • abnormal liver function tests
  • a high alanine transaminase level
  • a high aspartate transaminase level

If experienced, these tend to have a Less Severe expression i

  • excessive watery eyes
  • a stuffy and runny nose
  • excessive saliva production
  • backache
  • chills
  • abdominal bloating

RARE side effects

If experienced, these tend to have a Severe expression i

  • a bacterial infection
  • an infection due to a virus
  • an infection due to a fungus
  • low amount of sodium in the blood
  • decreased blood platelets
  • a low supply of oxygen rich blood to the heart
  • obstruction of a blood vessel by a blood clot
  • an occurrence of a blood clot in an artery
  • blood clot in a deep vein of the extremities
  • blood clot formation in vein
  • acute inflammation of the pancreas
  • a significant type of allergic reaction called anaphylaxis
  • a hypersensitivity reaction to a drug
  • lung tissue problem

If experienced, these tend to have a Less Severe expression i

  • itching
  • hives
  • difficulty sleeping
  • a type of speech disorder called dysarthria
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.