Zurampic

GENERIC NAME(S): Lesinurad

OTHER NAME(S): Zurampic Tablet

WARNINGS:

Lesinurad has caused very serious kidney problems, especially when it is used alone to lower uric acid levels. It should always be used in combination with another medication. If you need to stop your other uric acid medication, then you should also stop this medication. Consult your doctor for more details.

Who should not take Zurampic?

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Uses

Uses

Lesinurad is used with another medication (such as allopurinol, febuxostat) to lower uric acid levels in people with gout. It works by helping the kidneys get rid of uric acid from the body. Increased uric acid levels can cause gout.

How to use Zurampic

See also Warning section.

Read the Medication Guide provided by your pharmacist before you start taking lesinurad and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with food as directed by your doctor, usually once daily in the morning with your other uric acid medication. Drink a full glass of water with each dose and at least another 8 glasses (8 ounces each) a day while taking this drug. If you are on restricted fluid intake, consult your doctor for further instructions.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

You may have more gout attacks after starting this medicine while your body removes extra uric acid. Lesinurad is not a pain reliever. Your doctor may prescribe medication (including colchicine, NSAIDs such as ibuprofen, naproxen, or indomethacin) to prevent/treat a gout attack while you are taking lesinurad. Continue to take lesinurad and your prescribed medicines for gout attacks as directed by your doctor. Tell your doctor if your condition lasts or gets worse.

Side Effects

Side Effects

Heartburn may occur. If this effect lasts or gets worse, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: signs of kidney problems (such as lower back pain, painful/difficult urination, nausea/vomiting, change in the amount of urine).

A small number of people who took this medication had heart-related problems or stroke. However, it is not known if this medication caused these problems. Get medical help right away if you have any of these very serious side effects, including: weakness on one side of the body, sudden vision changes, confusion, chest/jaw/left arm pain, unusual sweating.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Precautions

Before taking lesinurad, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, cancer treatment, a certain inherited disease (Lesch-Nyhan syndrome).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

InteractionsOverdose

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Do not share this medication with others.

Lab and/or medical tests (such as kidney function, uric acid blood levels) should be done before you start taking this medication and while you are taking it. Keep all medical and lab appointments. Consult your doctor for more details.

Missed Dose

If you miss a dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.Information last revised September 2016. Copyright(c) 2016 First Databank, Inc.

Images

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.