IMFINZI Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • lung tissue problem

If experienced, these tend to have a Less Severe expression i

  • constipation
  • urinary tract infection
  • low energy
  • fluid retention in the legs, feet, arms or hands
  • decreased appetite
  • trouble breathing
  • cough
  • nausea
  • generalized weakness
  • intense abdominal pain
  • pain in the muscles or bones

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • overactive thyroid gland
  • low amount of sodium in the blood
  • anemia
  • decreased blood platelets
  • a decreased number of lymphocytes in the blood
  • pneumonia
  • inflammation of the large intestine
  • a type of kidney inflammation called interstitial nephritis
  • a hypersensitivity reaction to a drug
  • radiation pneumonitis
  • a high alanine transaminase level
  • a high aspartate transaminase level

If experienced, these tend to have a Less Severe expression i

  • a condition with low thyroid hormone levels
  • hair loss
  • fever
  • a change in voice
  • diarrhea
  • difficult or painful urination
  • night sweats

RARE side effects

If experienced, these tend to have a Severe expression i

  • a systemic inflammatory response called sepsis due to an infection with bacteria
  • meningitis not due to an infection
  • sarcoidosis
  • a bad infection
  • type 1 diabetes mellitus
  • diabetes
  • low levels of parathyroid hormone
  • pituitary hormone deficiency
  • decreased function of the adrenal gland
  • destruction of red blood cells by body's own antibodies
  • low platelet count and bleeding from immune response
  • an infection of the central nervous system called meningitis
  • encephalitis
  • inflammation of the iris - the colored part of the eyeball
  • inflammation of the uvea of the eye
  • inflammation of the cornea of the eye
  • inflammation of the covering of the heart or pericardium
  • inflammation of the middle tissue heart muscle
  • inflammation of the blood vessels
  • inflammation in the lungs due to an allergic reaction
  • liver inflammation resulting from an abnormal immune response
  • inflammation of the skin with blisters
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • muscle pain and stiffness in the shoulder, neck and pelvis
  • a condition with muscle tissue breakdown called rhabdomyolysis
  • muscle weakness
  • muscle inflammation
  • bone infection and inflammation
  • graft-versus-host disease
  • pancreatitis
  • inflammation of the pituitary gland
  • sepsis
  • histiocytic necrotizing lymphadenitis, a condition with swollen glands in the neck and flu symptoms
  • hemophagocytic lymphohistiocytosis, a condition where the body makes too many activated immune cells

If experienced, these tend to have a Less Severe expression i

  • a condition where portions of the skin lose the natural color called vitiligo
  • arthritis
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.