Cholinergics/Quinidine Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Quinidine may oppose the effects of the cholinergic medicine.

What might happen:

The cholinergic medicine may not work as well when taken with quinidine.Quinidine may prevent the slowing down of the heart that may occur with the cholinergic medicine.

What you should do about this interaction:

When taking these medicines together, the cholinergic medicine may not work as well. Contact your healthcare professionals (e.g. doctor or pharmacist) if you notice your condition getting worse.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Flacke W. Treatment of myasthenia gravis. N Engl J Med 1973 Jan 4; 288(1):27-31.
  • 2.Kornfeld P, Horowitz SH, Genkins G, Papatestas AE. Myasthenia gravis unmasked by antiarrhythmic agents. Mt Sinai J Med 1976 Jan-Feb;43(1):10-4.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.