Rifampin Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

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If experienced, these tend to have a Less Severe expression i

  • discoloration of the saliva
  • discolored sweat
  • sputum discoloration
  • an abnormal stool color
  • diarrhea
  • stomach cramps
  • INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

  • a skin rash
  • If experienced, these tend to have a Less Severe expression i

  • indigestion
  • RARE side effects

    If experienced, these tend to have a Severe expression i

  • diarrhea from an infection with Clostridium difficile bacteria
  • decreased function of the adrenal gland
  • porphyria
  • a type of blood disorder where the red blood cells burst called hemolytic anemia
  • acquired hemolytic anemia, an anemia due to destruction of red cells
  • anemia
  • a type of blood clotting disorder called disseminated intravascular coagulation
  • decreased blood-clotting from low vitamin K
  • increased risk of bleeding due to clotting disorder
  • large purple or brown skin blotches
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • mental problems from taking the drug
  • a disease with shrinking and weaker muscles called myopathy
  • inflammation of the blood vessels
  • low blood pressure
  • a type of inflammation of the lung called interstitial pneumonitis
  • bronchospastic lung disease
  • discoloration of teeth
  • liver damage
  • inflammation of the liver called hepatitis
  • blockage of normal bile flow
  • a type of kidney inflammation called interstitial nephritis
  • renal tubular necrosis, a kidney disorder
  • pemphigoid, a blistering skin disorder
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • high amount of bilirubin in the blood
  • swollen lymph nodes
  • trouble breathing
  • abnormal liver function tests
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • a hypersensitivity reaction to a drug
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
  • lung tissue problem
  • a type of skin disorder called acute generalized exanthematous pustulosis
  • a type of significant allergic skin reaction called DRESS syndrome
  • hemoglobinuria, a condition where hemoglobin is present in the urine
  • If experienced, these tend to have a Less Severe expression i

  • increased eosinophils in the blood
  • confusion
  • behavioral problems
  • a change in vision
  • pink eye
  • tear discoloration
  • a sore throat
  • a sore tongue
  • a problem with menstrual periods
  • muscle weakness
  • drowsiness
  • difficulty concentrating
  • dizziness
  • fever
  • low energy
  • pain
  • loss of muscle coordination
  • fluid retention in the legs, feet, arms or hands
  • temporary redness of face and neck
  • decreased appetite
  • headache
  • nausea
  • vomiting
  • heartburn
  • gas
  • abnormal color of urine
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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.