Rifampin Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Less Severe expression

  • An Abnormal Stool Color
  • Diarrhea
  • Discoloration Of The Saliva
  • Discolored Sweat
  • Sputum Discoloration
  • Stomach Cramps

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Skin Rash

If experienced, these tend to have a Less Severe expression

  • Indigestion
  • Inflammation Of The Skin Due To An Allergy
  • Itching

RARE side effects


If experienced, these tend to have a Severe expression

  • A Disease With Shrinking And Weaker Muscles Called Myopathy
  • A Hypersensitivity Reaction To A Drug
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome
  • A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis
  • A Type Of Allergic Reaction Called Angioedema
  • A Type Of Blood Clotting Disorder Called Disseminated Intravascular Coagulation
  • A Type Of Kidney Inflammation Called Interstitial Nephritis
  • A Type Of Significant Allergic Skin Reaction Called DRESS Syndrome
  • A Type Of Skin Disorder Called Acute Generalized Exanthematous Pustulosis
  • A Yellowing Of The Eyes Or Skin From Buildup Of Bilirubin Called Jaundice
  • Abnormal Liver Function Tests
  • Acquired Hemolytic Anemia, An Anemia Due To Destruction Of Red Cells
  • Anemia
  • Blockage Of Normal Bile Flow
  • Bronchospasm
  • Decreased Blood Platelets
  • Decreased Blood-Clotting From Low Vitamin K
  • Decreased Function Of The Adrenal Gland
  • Diarrhea From An Infection With Clostridium Difficile Bacteria
  • Discoloration Of Teeth
  • Erythema Multiforme, A Type Of Allergic Skin Reaction
  • Hemoglobinuria, A Condition Where Hemoglobin Is Present In The Urine
  • High Amount Of Bilirubin In The Blood
  • Increased Risk Of Bleeding Due To Clotting Disorder
  • Inflammation Of The Blood Vessels
  • Inflammation Of The Liver Called Hepatitis
  • Large Purple Or Brown Skin Blotches
  • Liver Damage
  • Low Blood Pressure
  • Low Levels Of A Type Of White Blood Cell Called Neutrophils
  • Low Levels Of White Blood Cells
  • Mental Problems From Taking The Drug
  • Pemphigoid, A Blistering Skin Disorder
  • Porphyria
  • Renal Tubular Necrosis, A Kidney Disorder
  • Swollen Lymph Nodes
  • Trouble Breathing
  • Very Low Levels Of Granulocytes, A Type Of White Blood Cell

If experienced, these tend to have a Less Severe expression

  • A Change In Vision
  • A Problem With Menstrual Periods
  • A Sore Throat
  • A Sore Tongue
  • Abnormal Color Of Urine
  • Behavioral Problems
  • Confusion
  • Decreased Appetite
  • Difficulty Concentrating
  • Dizziness
  • Drowsiness
  • Fever
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • Flu-Like Symptoms
  • Gas
  • Headache
  • Heartburn
  • Hives
  • Increased Eosinophils In The Blood
  • Loss Of Muscle Coordination
  • Low Energy
  • Muscle Weakness
  • Nausea
  • Pain
  • Pink Eye
  • Puffy Face From Water Retention
  • Tear Discoloration
  • Temporary Redness Of Face And Neck
  • Vomiting

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.