MKO (MIDAZOLAM-KETAMINE-ONDAN) Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • high blood pressure
  • spontaneous speaking or making vocal sounds
  • fast heartbeat
  • decreased lung function
  • If experienced, these tend to have a Less Severe expression i

  • confusion
  • delirium
  • hallucinations
  • constipation
  • drowsiness
  • fever
  • headache
  • diarrhea
  • a feeling of general discomfort called malaise
  • inducing of a relaxed easy state
  • INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

  • slow heartbeat
  • low blood pressure
  • decreased lung function
  • decreased oxygen in the tissues or blood
  • If experienced, these tend to have a Less Severe expression i

  • erythema or redness of skin or mucous membrane
  • an abnormal increase in muscle tone
  • drowsiness
  • memory loss
  • itching
  • dizziness
  • low energy
  • a skin rash
  • an inability to completely empty the bladder
  • generalized weakness
  • anxious feelings
  • agitation
  • hiccups
  • nausea
  • vomiting
  • RARE side effects

    If experienced, these tend to have a Severe expression i

  • an infection due to a virus
  • increased spinal fluid pressure
  • abnormal heart rhythm
  • a spasm of the larynx
  • excess liver fibrous tissue
  • liver damage
  • damage to the liver and inflammation
  • blockage of normal bile flow
  • inflammation of the bladder
  • bloody urine
  • apnea, a breathing interruption
  • abnormal liver function tests
  • a significant type of allergic reaction called anaphylaxis
  • inflammation of the liver with stoppage of bile flow
  • hydronephrosis, a swelling of the kidney due to urine build-up
  • extrapyramidal disease, a type of movement disorder
  • temporary blindness
  • a low supply of oxygen rich blood to the heart
  • a type of slowed heart rhythm disorder called heart block
  • abnormal heart electrical signals
  • supraventricular tachycardia
  • torsades de pointes, a type of abnormal heart rhythm
  • atrial fibrillation
  • ventricular premature beats
  • slow heartbeat
  • prolonged QT interval on EKG
  • low blood pressure
  • vocal cord swelling
  • bronchospasm
  • acute liver failure
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • a condition where the body is unable to maintain adequate blood flow called shock
  • trouble breathing
  • decreased oxygen in the tissues or blood
  • a type of allergic reaction called angioedema
  • fast heartbeat
  • painful and involuntary movement of the eyes called oculogyric crisis
  • over excitement
  • inflammation of the skin due to an allergy
  • itching
  • hives
  • delirium
  • muscle tremors
  • wheezing
  • an increase of carbon dioxide in the blood
  • nervousness
  • slow and shallow breathing
  • irritability
  • If experienced, these tend to have a Less Severe expression i

  • increased pressure in the eye
  • double vision
  • nystagmus, a condition with involuntary eye movements
  • muscle spasm
  • a skin rash
  • decreased appetite
  • nausea
  • difficult or painful urination
  • a condition where the urge to urinate results in urine leakage
  • an increased need to urinate often
  • reactions at the site of the injection
  • agitation
  • angina, a type of chest pain
  • dry mouth
  • hives
  • heart throbbing or pounding
  • hiccups
  • a feeling of pins and needles on skin
  • mood changes
  • aggressive behavior
  • blurred vision
  • a change in vision
  • excessive saliva production
  • drowsiness
  • fainting
  • sensation of spinning or whirling
  • dizziness
  • loss of muscle coordination
  • headache
  • a type of speech disorder called dysarthria
  • sneezing
  • an abnormal breathing sound called stridor
  • cough
  • runny nose
  • feelings of dissatisfaction, sadness, and unease
  • Drug Survey

    Are you currently using midazolam-ketamine-ondansetron sublingual?

    This survey is being conducted by the WebMD marketing sciences department.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.