BRAFTOVI Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • anemia
  • bleeding
  • a high alanine transaminase level
  • a high aspartate transaminase level

If experienced, these tend to have a Less Severe expression i

  • a skin rash resembling acne
  • joint pain
  • low energy
  • a skin rash
  • decreased appetite
  • nausea
  • vomiting
  • intense abdominal pain

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • squamous cell carcinoma
  • high amount of magnesium in the blood
  • low amount of sodium in the blood
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • a decreased number of lymphocytes in the blood
  • inflammation of the iris - the colored part of the eyeball
  • inflammation of the uvea of the eye
  • inflammation of the iris and ciliary body of the eye
  • bleeding within the skull
  • blood coming from anus
  • blood in the bowel movement
  • bleeding of the stomach or intestines
  • thickening of the outer horny layer of the skin
  • abnormal liver function tests
  • basal cell carcinoma of the skin
  • a type of slow growing skin cancer called a keratoacanthoma

If experienced, these tend to have a Less Severe expression i

  • constipation
  • itching
  • hair loss
  • dry skin
  • backache
  • pain in the arms or legs
  • dizziness
  • difficulty sleeping
  • fever
  • taste impairment
  • headache
  • diarrhea
  • high blood sugar
  • a type of mole called acquired melanocytic nevus

RARE side effects

If experienced, these tend to have a Severe expression i

  • prolonged QT interval on EKG
  • a hypersensitivity reaction to a drug
  • pancreatitis
  • an inflammatory condition of fat under the skin with red patches and lumps called panniculitis

If experienced, these tend to have a Less Severe expression i

  • paralysis of nerves for the face
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.