LORBRENA Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • anemia
  • abnormal liver function tests
  • a high alanine transaminase level
  • a high aspartate transaminase level

If experienced, these tend to have a Less Severe expression i

  • confusion
  • mood changes
  • joint pain
  • low energy
  • visible water retention
  • weight gain
  • diarrhea

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • mental problems from taking the drug
  • atrioventricular block, a type of slow heart rhythm disorder
  • pneumonia
  • a type of inflammation of the lung called interstitial pneumonitis
  • seizures

If experienced, these tend to have a Less Severe expression i

  • high cholesterol
  • backache
  • muscle pain
  • pain in the arms or legs
  • a sleep disorder
  • fever
  • a skin rash
  • aphasia, a loss of the ability to speak and understand language
  • a type of speech disorder called dysarthria

RARE side effects

If experienced, these tend to have a Severe expression i

  • suicidal thoughts
  • a heart attack
  • obstruction of a blood vessel by a blood clot
  • fluid in the lungs
  • acute respiratory distress syndrome, a type of lung disorder

If experienced, these tend to have a Less Severe expression i

    Sorry, we have no data available. Please contact your doctor or pharmacist.

    Drug Survey

    Are you currently using lorlatinib oral?

    This survey is being conducted by the WebMD marketing sciences department.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.