Does FLUOXETINE HCL Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SEROTONIN REUPTAKE INHIBITORS; SNRIS/SELECTED MAOIS
  • STRONG & MODERATE CYP2C19 INHIBITORS/MAVACAMTEN
  • SLT STRONG & MODERATE CYP2C19 INHIBITORS/CILOSTAZOL (> 50MG)
  • WEAK CYP3A4 INHIBITORS/LOMITAPIDE (>40MG)
  • SEROTONINERGIC AGENTS/DAPOXETINE
  • STRONG CYP2D6 INHIBITORS/PIMOZIDE
  • SELECTED SSRIS; DULOXETINE/THIORIDAZINE
  • SEROTONINERGIC AGENTS/SIBUTRAMINE
  • SEROTONINERGIC AGENTS/DEXFENFLURAMINE; FENFLURAMINE
  • SSRIS; NEFAZODONE/ASTEMIZOLE; TERFENADINE
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SEROTONIN REUPTAKE INHIBITORS/LINEZOLID
  • SELECTED CYP2D6 SUBSTRATES/PANOBINOSTAT
  • AGENTS THAT AFFECT CATECHOLAMINES/IOBENGUANE I 123
  • AGENTS THAT AFFECT CATECHOLAMINES/IOBENGUANE I 131
  • SLT STRONG 2D6 INHIBITOR/ARIPIPRAZOLE LAUROXIL SUBMICRONIZED
  • WEAK CYP3A4 INHIBITORS/LOMITAPIDE (>30MG OR <=40MG)
  • STRONG & MODERATE CYP2D6 INHIBITORS/ELIGLUSTAT
  • FLUOXETINE;PAROXETINE/HIGHER STRENGTH TRICYCLICS;TRAZODONE
  • FLUOXETINE; PAROXETINE/DEXTROMETHORPHAN AND QUINIDINE
  • CLOMIPRAMINE; IMIPRAMINE; SSRIS; SNRIS;/MEPERIDINE
  • SELECT CYP2C19 INHIBITORS/CITALOPRAM (>20 MG)
  • DOPAMINE TRANSPORTER BINDERS/IOFLUPANE I 123
  • FLUOXETINE; FLUVOXAMINE/CLOPIDOGREL
  • SSRIS; SNRIS/METOCLOPRAMIDE
  • SELECTED STRONG CYP2D6 INHIBITORS/TAMOXIFEN
  • STRONG 2D6 INHIBITORS/ATOMOXETINE; VORTIOXETINE
  • SSRIS; SNRIS/SELECTED ANTICOAGULANTS (VITAMIN K ANTAGONISTS)
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SSRIS; SNRIS/SELECTED NSAIDS; ASPIRIN
  • SELECTED CYP2D6 SUBSTRATES/TERBINAFINE
  • SSRIS;SNRIS/SLT ANTICOAGULANTS;ANTIPLATELETS;THROMBOLYTICS
  • SELECT SEROTONERGIC AGENTS/FENTANYL
  • SSRIS; VILAZODONE/FLURBIPROFEN
  • SSRIS; VILAZODONE/SELECTED NSAIDS
  • SELECTED CYP1A2 OR CYP2D6 SUBSTRATES/GIVOSIRAN
  • SELECTED SSRIS;SNRIS/CILOSTAZOL; TICLOPIDINE
  • SELECTED STRONG CYP2C19 INHIBITORS/ABROCITINIB
  • STRONG CYP2C19 INHIBITORS/BELZUTIFAN
  • STRONG CYP2D6 INHIBITORS/MEXILETINE
  • STRONG CYP2D6 OR CYP3A4 INHIBITORS/OLICERIDINE
  • STRONG CYP2D6 INHIBITORS/PITOLISANT
  • SLT STRONG & MODERATE CYP2C19 INHIBITORS/CILOSTAZOL (<=50MG)
  • FLUOXETINE; SERTRALINE/CLOZAPINE
  • SELECTED CYP2D6 INHIBITORS/METOPROLOL
  • SNRIS; SSRIS/BUPROPION
  • AGENTS WITH HYPONATREMIA RISK/DESMOPRESSIN
  • SELECTED CYP2C19 INHIBITORS/ESCITALOPRAM (<= 15 MG)
  • AGENTS WITH HYPONATREMIA RISK/DESMOPRESSIN (NOCTURIA)
  • STRONG CYP2D6 INHIBITORS/OXYCODONE
  • STRONG 2D6 INHIBITORS/VALBENAZINE
  • FLUOXETINE/ALPRAZOLAM
  • SELECTED STRONG CYP2D6 INHIBITORS/FLECAINIDE
  • STRONG CYP2D6 INHIBITORS/BREXPIPRAZOLE
  • SELECTED STRONG CYP2D6 INHIBITORS/ILOPERIDONE
  • FLUOXETINE; PAROXETINE/LOWER STRENGTH TRICYCLICS; TRAZODONE
  • FLUOXETINE; PAROXETINE/DEXTROMETHORPHAN
  • FLUOXETINE; PAROXETINE/DULOXETINE
  • SELECTED CYP2C19 INHIBITORS/ESCITALOPRAM (> 15 MG)
  • WEAK CYP3A4 INHIBITORS/LOMITAPIDE (<=30MG)
  • FLUOXETINE; FLUVOXAMINE/HALOPERIDOL
  • SELECTED MODERATE CYP2C19 INHIBITORS/CLOBAZAM
  • SELECTED MODERATE TO STRONG CYP2D6 INHIBITORS/TRAMADOL
  • SELECTED CYP2C19 INHIBITORS/CITALOPRAM (<= 20 MG)
  • STRONG CYP2D6 INHIBITORS/DEUTETRABENAZINE;TETRABENAZINE
  • FLUOXETINE/NEBIVOLOL
  • SSRIS; SNRIS/AMPHETAMINES; PHENTERMINE
  • SELECTED SSRIS/PERHEXILINE
  • SELECT STRONG CYP2D6 INHIBITORS/ARIPIPRAZOLE
  • SSRIS; SNRIS/LITHIUM
  • DULOXETINE; FLUOXETINE; PAROXETINE/RISPERIDONE
  • FLUOXETINE/PROPAFENONE
  • STRONG CYP2D6 INHIBITORS/CODEINE
  • SSRIS; SNRIS/TAPENTADOL
  • FLUOXETINE/HYDANTOINS
  • SELECTED SSRIS/CARBAMAZEPINE
  • FLUOXETINE; NEFAZODONE/SELECTED BENZODIAZEPINES
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    Drug Survey

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.