ZIRABEV Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • high blood pressure
  • blood clot formation in vein
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • blood coming from anus
  • bleeding of the stomach or intestines
  • skin rash with sloughing
  • trouble breathing
  • elevation of proteins in the urine
  • secondary ovarian failure, a condition where ovaries stop working before age 40

If experienced, these tend to have a Less Severe expression i

  • excessive watery eyes
  • a common cold
  • a stuffy and runny nose
  • dry skin
  • joint pain
  • backache
  • muscle pain
  • dizziness
  • low energy
  • taste impairment
  • decreased appetite
  • headache
  • nausea
  • vomiting
  • diarrhea
  • stomach cramps
  • generalized weakness
  • peripheral sensory nerve disorder

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • low amount of magnesium in the blood
  • low amount of sodium in the blood
  • dehydration
  • decreased blood platelets
  • a blood clot
  • blood clot in a deep vein of the extremities
  • low blood pressure
  • stomach or intestinal ulcer
  • inflammation of the large intestine
  • blocked bowels with decreased peristaltic movement
  • decreased kidney function
  • a skin ulcer
  • fainting
  • chest pain
  • a hypersensitivity reaction to a drug

If experienced, these tend to have a Less Severe expression i

  • a decreased number of lymphocytes in the blood
  • angina, a type of chest pain
  • hemorrhoids
  • nasal passage irritation
  • dry mouth
  • indigestion
  • constipation
  • soreness of the rectal area
  • hair loss
  • muscle weakness
  • pain
  • weight loss
  • a change in voice
  • a type of speech disorder called dysarthria
  • pelvic pain
  • runny nose

RARE side effects

If experienced, these tend to have a Severe expression i

  • low amount of potassium in the blood
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • inflammation of the inside of the eye
  • detachment of the retina of the eye
  • hemorrhage from the conjunctiva of the eye
  • extremely high blood pressure
  • a heart attack
  • pulmonary hypertension
  • chronic heart failure
  • a hemorrhage in the brain
  • a transient ischemic attack, a type of stroke that lasts only a few minutes
  • a stroke
  • cerebral ischemia, a lack of blood supply to the brain
  • a localized weakening and ballooning in an artery wall called an arterial aneurysm
  • an occurrence of a blood clot in an artery
  • thrombotic thrombocytopenic purpura, a type of blood disorder
  • bleeding from varicose veins or varices in the esophagus
  • bleeding
  • perforation of the wall that divides the nose
  • an abnormal connection between the esophagus and windpipe
  • a decrease in blood supply to the intestines resulting in portions of the intestine dying
  • a gastrointestinal tract fistula
  • nephrotic syndrome, a type of kidney disorder
  • bleeding not related to menstrual period
  • coughing up of blood
  • bloody vomit
  • impaired wound healing
  • a significant type of allergic reaction called anaphylaxis
  • a rupture in the wall of the stomach or intestine
  • problems with wound healing after a surgery
  • bleeding from the lungs
  • portions of the jaw bone to die from lack of blood circulation
  • a type of brain disorder called posterior reversible encephalopathy syndrome
  • dissection of the aorta
  • a fistula between two body organs
  • a hole in the wall of the gallbladder
  • necrotizing fasciitis
  • inflammation of the serous membranes in the body
  • an acute blockage of the mesenteric vein
  • dissection of artery

If experienced, these tend to have a Less Severe expression i

  • blurred vision
  • eye inflammation
  • wheezing
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.