What should I Know Regarding Pregnancy, Nursing and Administering Xpovio 100 Mg/Week (20 Mg X 5) Tablet Antineoplastic-Selective Inhibitors Of Nuclear Export(SINE) to Children or the Elderly?
If you are PREGNANT
If you are NURSING
- Absolute Contraindication: NOT RECOMMENDED; POTENTIAL FOR SERIOUS ADVERSE EFFECTS IN INFANT.
If you are an adult over 60
- management or monitoring precaution: General-When comparing patients 75 years of age and older to younger patients, older patients had a higher incidence of discontinuation due to an ADR (44% vs 27%), higher incidence of serious ADRs (70% vs 58%), and higher incidence of fatal ADRs (17% vs 9%). Gastrointestinal-Anorexia may occur. Median time to onset is 8 days. Monitor patient more frequently during first two months of treatment.
Giving Xpovio 100 Mg/Week (20 Mg X 5) Tablet Antineoplastic-Selective Inhibitors Of Nuclear Export(SINE) to a child under 12
- management or monitoring precaution: Safety and effectiveness have not been established in pediatric patients.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.