TRUXIMA Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • a systemic inflammatory response called sepsis due to an infection with bacteria
  • an infection
  • decreased blood platelets
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • a decreased number of lymphocytes in the blood
  • a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
  • low blood pressure
  • a stuffy and runny nose
  • bronchospasm
  • itching
  • fever
  • low energy
  • chills
  • a skin rash
  • temporary redness of face and neck
  • trouble breathing
  • nausea
  • vomiting
  • a type of allergic reaction called angioedema
  • a type of immune system problem called hypogammaglobulinemia

If experienced, these tend to have a Less Severe expression i

  • a common cold
  • bronchitis
  • constipation
  • urinary tract infection
  • hair loss
  • backache
  • muscle spasm
  • headache
  • cough
  • a feeling of pins and needles on skin
  • generalized weakness
  • night sweats

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • a systemic inflammatory response called sepsis due to an infection with fungus
  • shingles
  • low amount of phosphate in the blood
  • anemia
  • high blood pressure
  • inflammation of the tissue lining the sinuses
  • hives
  • fluid retention in the legs, feet, arms or hands
  • breathing changes
  • chest tightness
  • reactions at the site of the injection

If experienced, these tend to have a Less Severe expression i

  • a herpes simplex infection
  • depression
  • pink eye
  • a sore throat
  • indigestion
  • joint pain
  • muscle pain
  • dizziness
  • difficulty sleeping
  • pain
  • weight gain
  • diarrhea
  • abdominal bloating
  • irritability
  • a small, soft skin growth called cutaneous papilloma
  • pain in the muscles or bones
  • anxious feelings

RARE side effects

If experienced, these tend to have a Severe expression i

  • an infection due to a virus
  • pneumonia with a fungus called Pneumocystis jirovecii
  • high amount of phosphate in the blood
  • low amount of calcium in the blood
  • high levels of potassium in the blood
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • a decrease in bone marrow production
  • inflammation of the uvea of the eye
  • sudden blindness and pain upon moving the eye
  • a heart attack
  • angina, a type of chest pain
  • ventricular fibrillation, a heart rhythm disorder
  • abnormal heart rhythm
  • supraventricular arrhythmias, a type of abnormal heart rhythm
  • heart failure
  • inflammation of the blood vessels
  • a type of lung condition called bronchiolitis obliterans
  • pneumonia
  • pleuritis, a condition where the covering of the lung becomes inflamed
  • x-ray results showing lung tissue changes
  • acute respiratory distress syndrome, a type of lung disorder
  • blocked bowels with decreased peristaltic movement
  • blockage of the stomach or intestine
  • a hole in the intestine
  • liver failure
  • damage to the kidneys
  • acute kidney failure
  • pyoderma gangrenosum, a condition where large painful skin sores form
  • inflammation of the skin with blisters
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • a condition with symptoms that resemble lupus
  • muscle weakness of the arms or legs
  • blood circulation failure due to serious heart condition
  • decreased oxygen in the tissues or blood
  • a significant type of allergic reaction called anaphylaxis
  • a hypersensitivity reaction to a drug
  • a serum sickness reaction
  • a rupture in the wall of the stomach or intestine
  • lung tissue problem
  • reactivation of hepatitis B infection
  • progressive multifocal leukoencephalopathy, a type of brain infection
  • a type of brain disorder called posterior reversible encephalopathy syndrome
  • paraneoplastic pemphigus, a blistering skin condition associated with cancer
  • a type of drug-related rash called lichenoid dermatitis
  • tumor lysis syndrome

If experienced, these tend to have a Less Severe expression i

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.