COMMON side effects

If experienced, these tend to have a Severe expression i

• a systemic inflammatory response called sepsis due to an infection with bacteria
• an infection
• decreased blood platelets
• low levels of white blood cells
• low levels of a type of white blood cell called neutrophils
• a decreased number of lymphocytes in the blood
• a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
• low blood pressure
• a stuffy and runny nose
• bronchospasm
• itching
• fever
• low energy
• chills
• a skin rash
• temporary redness of face and neck
• trouble breathing
• nausea
• vomiting
• a type of allergic reaction called angioedema
• a type of immune system problem called hypogammaglobulinemia

If experienced, these tend to have a Less Severe expression i

• a common cold
• bronchitis
• constipation
• urinary tract infection
• hair loss
• backache
• muscle spasm
• headache
• cough
• a feeling of pins and needles on skin
• generalized weakness
• night sweats

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

• a systemic inflammatory response called sepsis due to an infection with fungus
• shingles
• low amount of phosphate in the blood
• anemia
• high blood pressure
• inflammation of the tissue lining the sinuses
• hives
• fluid retention in the legs, feet, arms or hands
• breathing changes
• chest tightness
• reactions at the site of the injection

If experienced, these tend to have a Less Severe expression i

• a herpes simplex infection
• depression
• pink eye
• a sore throat
• indigestion
• joint pain
• muscle pain
• dizziness
• difficulty sleeping
• pain
• weight gain
• diarrhea
• abdominal bloating
• irritability
• a small, soft skin growth called cutaneous papilloma
• pain in the muscles or bones
• anxious feelings

RARE side effects

If experienced, these tend to have a Severe expression i

• an infection due to a virus
• pneumonia with a fungus called Pneumocystis jirovecii
• high amount of phosphate in the blood
• low amount of calcium in the blood
• high levels of potassium in the blood
• a type of blood disorder with a decrease in all types of blood cells called pancytopenia
• a decrease in bone marrow production
• inflammation of the uvea of the eye
• sudden blindness and pain upon moving the eye
• a heart attack
• angina, a type of chest pain
• ventricular fibrillation, a heart rhythm disorder
• abnormal heart rhythm
• supraventricular arrhythmias, a type of abnormal heart rhythm
• heart failure
• inflammation of the blood vessels
• a type of lung condition called bronchiolitis obliterans
• pneumonia
• pleuritis, a condition where the covering of the lung becomes inflamed
• x-ray results showing lung tissue changes
• acute respiratory distress syndrome, a type of lung disorder
• blocked bowels with decreased peristaltic movement
• blockage of the stomach or intestine
• a hole in the intestine
• liver failure
• damage to the kidneys
• acute kidney failure
• pyoderma gangrenosum, a condition where large painful skin sores form
• inflammation of the skin with blisters
• a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
• a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
• a condition with symptoms that resemble lupus
• muscle weakness of the arms or legs
• blood circulation failure due to serious heart condition
• decreased oxygen in the tissues or blood
• a significant type of allergic reaction called anaphylaxis
• a hypersensitivity reaction to a drug
• a serum sickness reaction
• a rupture in the wall of the stomach or intestine
• lung tissue problem
• reactivation of hepatitis B infection
• progressive multifocal leukoencephalopathy, a type of brain infection
• a type of brain disorder called posterior reversible encephalopathy syndrome
• paraneoplastic pemphigus, a blistering skin condition associated with cancer
• a type of drug-related rash called lichenoid dermatitis
• tumor lysis syndrome

If experienced, these tend to have a Less Severe expression i