How to use Tezspire 210 Mg/1.91 Ml (110 Mg/Ml) Subcutaneous Syringe Asthma Therapy - Thymic Stromal Lymphopoietin Inhibitor, Mab

Read the Patient Information Leaflet and Instructions for Use if available from your pharmacist before you start using tezepelumab and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

This medication is given by injection under the skin of the upper arm, thigh, or abdomen as directed by your doctor, usually once every 4 weeks.

If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the product package. Wash your hands before using this medication. Remove the medication from the refrigerator at least 60 minutes before you inject it to allow it to reach room temperature. Do not warm up this medication any other way such as by heating in the microwave, placing in hot water, or leaving it in direct sunlight. Do not shake the medication. The medication should be colorless to light yellow. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Do not inject into skin that is tender, bruised, red, hard, or damaged. To lessen bruising, do not rub the injection site after a shot. Learn how to store and discard medical supplies safely.

If you are regularly using a corticosteroid medication, you should not stop using it unless directed by your doctor. Some conditions (such as asthma, allergies) may become worse when the drug is suddenly stopped. If you suddenly stop using the corticosteroid medication, you may also have withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, dizziness). To help prevent withdrawal, your doctor may slowly lower the dose of your corticosteroid medication after you begin using tezepelumab. Tell your doctor or pharmacist right away if you have withdrawal.

Use this medication regularly to get the most benefit from it. To help you remember, mark your calendar when you need to use it each month.

Tell your doctor if your condition does not get better or if it gets worse.

Side Effects

Pain, redness, or swelling at the injection site may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before using tezepelumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: infection due to a parasite (helminth).

Tell your health care professional that you are using tezepelumab before having any immunizations/vaccinations. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

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Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes Notes

Keep all medical and lab appointments.

Missed Dose Missed Dose

It is important to get each dose of this medication as scheduled. If your dose is given by a health care professional and you miss a dose, ask your doctor right away for a new dosing schedule. If you are using this medication at home and miss a dose, use it as soon as you remember. Use your next dose on the regular day. Do not double the dose to catch up.

Storage Storage

Store in the refrigerator. Do not freeze. This medication may also be stored at room temperature for up to 30 days. If this medication is brought to room temperature, do not put it back in the refrigerator. Keep the product in the original carton to protect from light. Discard any medication that has been stored at room temperature for more than 30 days.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.