Does Heartburn 200 Oral Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • MODERATE CYP3A4 INHIBITORS/LUMATEPERONE (>21 MG)
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LONAFARNIB
  • SLT STRONG & MODERATE CYP3A4 INHIBITORS/CILOSTAZOL (>50MG)
  • SELECTED CYP3A4 MODERATE INHIBITORS/LURASIDONE (> 80 MG)
  • WEAK CYP3A4 INHIBITORS/LOMITAPIDE (>40MG)
  • MODERATE CYP3A4 INHIBITORS/NALOXEGOL (> 12.5 MG)
  • MODERATE CYP3A4 INHIBITORS/AVANAFIL (> 50 MG)
  • CIMETIDINE/EPIRUBICIN
  • CIMETIDINE/CISAPRIDE
  • CIMETIDINE/DOFETILIDE
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED MATE SUBSTRATES/RISDIPLAM
  • DUAL WEAK CYP2C19 & MODERATE CYP3A4 INHIBITORS/MAVACAMTEN
  • DUAL CYP3A4 & WEAK CYP2D6 INHIBITORS/ELIGLUSTAT
  • MODERATE CYP3A4 INHIBITORS/PACRITINIB
  • H2 ANTAGONISTS; PROTON PUMP INHIBITORS/LEVOKETOCONAZOLE
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/BILASTINE
  • MODERATE CYP3A4 INHIBITORS/MOBOCERTINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/DOXORUBICIN
  • CIMETIDINE/PEXIDARTINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/FEXINIDAZOLE
  • H2 ANTAGONISTS;PROTON PUMP INHIBITORS/METHYLPHENIDATE XR-ODT
  • H2 ANTAGONISTS; PROTON PUMP INHIBITORS/SOTORASIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/INFIGRATINIB
  • SELECTED MODERATE CYP3A4 INHIBITORS/ALPRAZOLAM
  • ANTICHOLINERGICS; OPIOIDS/ELUXADOLINE
  • CIMETIDINE/CHLOROQUINE; HYDROXYCHLOROQUINE
  • MODERATE CYP3A4 INHIBITORS/VOCLOSPORIN
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/RELUGOLIX
  • ANTICHOLINERGICS/ZONISAMIDE
  • LONG ACTING ANTACIDS; H2S;PPIS/SELECTED CEPHALOSPORINS
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LURBINECTEDIN
  • MODERATE CYP3A4 INHIBITORS/SELPERCATINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/PEMIGATINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/SELUMETINIB
  • ANTICHOLINERGICS/CLOZAPINE
  • MODERATE CYP3A4 INHIBITORS/TAZEMETOSTAT
  • CIMETIDINE/BOSUTINIB
  • CIMETIDINE/NERATINIB
  • MODERATE CYP3A4 INHIBITORS/ELEXACAFTOR-TEZACAFTOR-IVACAFTOR
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/ORAL LEFAMULIN
  • MODERATE CYP3A4 INHIBITORS/ENTRECTINIB
  • H2 ANTAGONISTS; PROTON PUMP INHIBITORS/SECRETIN
  • MODERATE CYP3A4 INHIBITORS/BRIGATINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/TALAZOPARIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/ENCORAFENIB
  • H2 ANTAGONISTS/DASATINIB; PAZOPANIB
  • CIMETIDINE; DOLUTEGRAVIR/DALFAMPRIDINE
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/COLCHICINE
  • MODERATE CYP3A4 INHIBITORS/VENETOCLAX
  • WEAK CYP3A4 INHIBITORS/LOMITAPIDE (>30MG OR <=40MG)
  • MODERATE CYP3A4 INHIBITORS/NALOXEGOL (<= 12.5 MG)
  • MODERATE CYP3A4 INHIBITORS/SUVOREXANT (> 10 MG)
  • MODERATE CYP3A4 INHIBITORS/ERGOT ALKALOIDS
  • SELECTED MODERATE CYP3A4 INHIBITORS/PIMOZIDE
  • STRONG & MODERATE CYP3A4 INHIBITORS/GUANFACINE
  • STRONG OR MODERATE CYP3A4 INHIBITORS/SIMEPREVIR
  • SELECT CYP2C19 INHIBITORS/CITALOPRAM (>20 MG)
  • ESOMEPRAZOLE; OMEPRAZOLE; CIMETIDINE/CLOPIDOGREL
  • ANTICHOLINERGICS/SOLID ORAL POTASSIUM CAPSULES
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/TOPOTECAN
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/DABIGATRAN
  • CIMETIDINE; PROTON PUMP INHIBITORS/POSACONAZOLE SUSPENSION
  • CIMETIDINE; FAMOTIDINE/TIZANIDINE
  • ANTICHOLINERGICS/SOLID ORAL POTASSIUM TABLETS
  • MODERATE CYP3A4 INHIBITORS/IVABRADINE
  • CIMETIDINE/TACRINE
  • CIMETIDINE/THEOPHYLLINE DERIVATIVES
  • CIMETIDINE/CARMUSTINE
  • CIMETIDINE/SELECTED ANTICOAGULANTS (VIT K ANTAGONISTS)
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • CIMETIDINE/PROCAINAMIDE
  • CIMETIDINE/BENZODIAZEPINES
  • CIMETIDINE/ACALABRUTINIB TABLETS
  • MODERATE CYP3A4 INHIBITORS/LUMATEPERONE (<=21 MG)
  • SLT MODERATE AND WEAK CYP3A4 INHIBIT/SIROLIMUS PROTEIN-BOUND
  • P-GP OR BCRP INHIBITORS/BEROTRALSTAT
  • ANTICHOLINERGICS/TOPIRAMATE
  • MODERATE CYP3A4 INHIBITORS/RIMEGEPANT
  • MODERATE CYP3A4 INHIBITORS/AVAPRITINIB
  • MODERATE CYP3A4 INHIBITORS/UBROGEPANT
  • MODERATE AND WEAK CYP3A4 INHIBITORS/TACROLIMUS
  • CIMETIDINE/ACALABRUTINIB CAPSULES
  • MODERATE CYP3A4 INHIBITORS/ZANUBRUTINIB
  • SELECTED CYP3A4 MODERATE INHIBITORS/LURASIDONE (<= 80 MG)
  • MODERATE CYP3A4 INHIBITORS/ABEMACICLIB
  • SELECTED MODERATE CYP3A4 INHIBITORS/IVOSIDENIB
  • SELECTED CYP2C19 INHIBITORS/ESCITALOPRAM (<= 15 MG)
  • SELECT P-GP INHIBITORS/EDOXABAN (<= 30 MG)
  • MODERATE CYP3A4 INHIBITORS/CABERGOLINE
  • SEL ORAL CATIONS; ANTACIDS; H2 ANTAG/DOLUTEGRAVIR-RILPIVIRIN
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/BETRIXABAN
  • H2 ANTAGONISTS/SELECTED KINASE INHIBITORS
  • MODERATE CYP3A4 INHIBITORS/QUETIAPINE
  • MODERATE CYP3A4 INHIBITORS/BROMOCRIPTINE
  • SELECT P-GP INHIBITORS/EDOXABAN (> 30 MG)
  • MODERATE CYP3A4 INHIBITORS/BREXPIPRAZOLE
  • P-GP AND MODERATE CYP3A4 INHIBITORS/APIXABAN
  • P-GP AND SELECTED CYP3A4 INHIBITORS/NINTEDANIB
  • ANTACIDS; H2 ANTAGONISTS/LEDIPASVIR; VELPATASVIR
  • MODERATE CYP3A4 INHIBITORS/SUVOREXANT (<= 10 MG)
  • MODERATE CYP3A4 INHIBITORS/AVANAFIL (<= 50 MG)
  • MODERATE CYP3A4 INHIBITORS/IBRUTINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/AFATINIB
  • SELECTED CYP2C19 INHIBITORS/ESCITALOPRAM (> 15 MG)
  • WEAK CYP3A4 INHIBITORS/LOMITAPIDE (<=30MG)
  • CIMETIDINE/ZOLMITRIPTAN (> 2.5 MG)
  • SELECTED CYP2C19 INHIBITORS/CITALOPRAM (<= 20 MG)
  • SELECTED P-GP AND WEAK CYP3A4 INHIBITORS/RIVAROXABAN
  • ANTACIDS; H2 ANTAGONISTS/RILPIVIRINE
  • MODERATE CYP3A4; P-GP INHIBITORS/EVEROLIMUS
  • SELECTED WEAK CYP2D6 INHIBITORS/TAMOXIFEN
  • ANTACIDS;H2 ANTAGONISTS;PROTON PUMP INHIBITORS/AMPHETAMINES
  • CYP3A4; CYP2C8; P-GLYCOPROTEIN (P-GP) INHIBITORS/LOPERAMIDE
  • CIMETIDINE/MOCLOBEMIDE
  • CIMETIDINE/METFORMIN
  • H2 ANTAGONISTS/ATAZANAVIR
  • CIMETIDINE/MORICIZINE
  • CIMETIDINE/ZALEPLON
  • CIMETIDINE/SELECTED OPIOID ANALGESICS
  • SLT STRONG & MODERATE CYP3A4 INHIBITORS/CILOSTAZOL (<=50MG)
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/ETOPOSIDE
  • CIMETIDINE/SELECTED CALCIUM CHANNEL BLOCKERS
  • CIMETIDINE/TRICYCLIC COMPOUNDS
  • CIMETIDINE/CARBAMAZEPINE
  • AGENTS AFFECTING GASTRIC PH/ITRACONAZOLE; KETOCONAZOLE
  • CIMETIDINE/METOPROLOL; PROPRANOLOL
  • CIMETIDINE; RANITIDINE/HYDANTOINS
  • CIMETIDINE/QUINIDINE
  • CIMETIDINE/LIDOCAINE
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    Drug Survey

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.