Selected BCRP Substrates/Safinamide Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Safinamide may increase the amount of medicine your body absorbs.

What might happen:

The amount of your other medicine in your blood may increase and it may cause more side effects than expected.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. If you are unsure of when to take your medicines, ask your pharmacist. Let your doctor know if you have any side effects from your medicine.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Xadago (safinamide) EMA summary of product characteristics. Zambon S.p.A. October 30, 2019.
  • 2.Xadago (safinamide) US prescribing information. US WorldMeds, LLC November, 2019.
  • 3.European Medicines Agency (EMA). Xadago: EPAR - Procedural steps taken and scientific information after the authorisation. Accessed at: procedural-steps-taken-scientific-information-after-authorisation_en.pdf October 30, 2019.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.