Interactions

Kaletra Solution may interact with the following medications:

Severe Interactions of Kaletra Solution:

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

• SELECTED PROTEASE INHIBITORS/FLECAINIDE; PROPAFENONE
• PROTEASE INHIBITORS/MIDAZOLAM; TRIAZOLAM
• RITONAVIR/PROPOXYPHENE
• SELECTED 3A4 INHIBITORS/PIMOZIDE
• PROTEASE INHIBITORS/ERGOT DERIVATIVES
• SELECTED 3A4 SUBSTRATES/RIFAMPIN
• SELECTED 3A4 SUBSTRATES/ST. JOHN'S WORT
• LOPINAVIR/TIPRANAVIR
• STRONG OR MODERATE CYP3A4 INHIBITORS/LOMITAPIDE
• OATP1B1-3 INHIBITORS/ELBASVIR-GRAZOPREVIR
• STRONG CYP3A4 INHIBITORS/PANOBINOSTAT (> 10 MG)
• STRONG CYP3A4 INHIBITORS/NALOXEGOL
• STRONG CYP3A4 INHIBITORS/AVANAFIL
• 3A4INHIB/DAPOXETINE;LEVOMILNACIPRAN(>80MG);VILAZODONE(>20MG)
• STRONG OR MODERATE CYP3A4 INHIBITORS/FLIBANSERIN
• PROTEASE INHIBITORS & NNRTIS/COBICISTAT-ELVITEGRAVIR
• STRONG CYP3A4 INHIBITORS/SLT HIGH STRENGTH ANTIMUSCARINICS
• SELECTED STRONG CYP3A4 INHIBITORS/DOMPERIDONE; CISAPRIDE
• STRONG CYP3A4 INHIBITORS/TICAGRELOR
• SELECTED PROTEASE INHIBITORS; COBICISTAT/LURASIDONE
• HIV PROTEASE INHIBITORS; COBICISTAT/SILDENAFIL (FOR PAH)
• STRONG CYP3A4 INHIBITORS/SAXAGLIPTIN (> 2.5 MG)
• STRONG CYP3A4 INHIBITORS/DRONEDARONE
• ATAZANAVIR; LOPINAVIR; SIMEPREVIR/ROSUVASTATIN (> 10 MG)
• P-GP AND STRONG CYP3A4 INHIBITORS/RIVAROXABAN
• STRONG CYP3A4 INHIBITORS/RANOLAZINE
• STRONG CYP3A4 INHIBITORS/TOLVAPTAN
• STRONG CYP3A4 INHIBITORS/IVABRADINE
• PROTEASE INHIBITORS/ALFUZOSIN;SILODOSIN;TAMSULOSIN
• SELECTED PROTEASE INHIBITORS/VARDENAFIL
• STRONG CYP3A4 INHIBITORS/EPLERENONE
• STRONG CYP3A4 INHIBITORS/IRINOTECAN
• SELECTED PROTEASE INHIBITORS; COBICISTAT/ELETRIPTAN
• SELECTED 3A4 INHIBITORS/LOVASTATIN; SIMVASTATIN

Serious Interactions of Kaletra Solution:

These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

• SELECTED PROTEASE INHIBITORS/CONTRACEPTIVES
• SELECTED PROTEASE INHIBITORS/RIFABUTIN; RIFAPENTINE
• PROTEASE INHIBITORS/CARBAMAZEPINE
• SELECTED PROTEASE INHIBITORS/GARLIC
• SELECTED PROTEASE INHIBITORS/ETRAVIRINE
• LOPINAVIR/QT PROLONGING AGENTS
• RITONAVIR & RITONAVIR-BOOSTED PROTEASE INHIBITORS/BOCEPREVIR
• SELECTED OATP INHIBITORS/VOXILAPREVIR
• STRONG AND MODERATE CYP3A4 INHIBITORS/NERATINIB
• STRONG CYP3A4 INHIBITORS/BRIGATINIB
• STRONG CYP3A4 INHIBITORS/VALBENAZINE
• STRONG CYP3A4 INHIBITORS/RIBOCICLIB
• MODERATE CYP3A4 INDUCERS/VENETOCLAX
• STRONG AND MODERATE CYP3A4 INHIBITORS/DEFLAZACORT
• SELECTED ANTIRETROVIRALS/ORLISTAT
• STRONG CYP3A4 INHIBITORS/PIMAVANSERIN
• STRONG CYP3A4 INHIBITORS/VENETOCLAX
• STRONG CYP3A4 INHIBITORS/VEMURAFENIB
• STRONG CYP3A4 INHIBITORS/OSIMERTINIB
• STRONG CYP3A4 INHIBITORS/TRABECTEDIN
• STRONG CYP3A4 INHIBITORS/CARIPRAZINE
• OATP1B1 INHIBITORS/ELUXADOLINE
• STRONG CYP3A4 INHIBITORS/BEDAQUILINE; DELAMANID
• STRONG CYP3A4 INHIBITORS/LUMACAFTOR-IVACAFTOR
• RITONAVIR/ISAVUCONAZONIUM
• STRONG CYP3A4 INHIBITORS/SELECTED ANTINEOPLASTICS
• STRONG 3A4 INHIB/ESZOPICLONE>2MG; ZOPICLONE>5 MG; SUVOREXANT
• STRONG & MODERATE CYP3A4 INHIBITORS/ELIGLUSTAT
• STRONG CYP3A4 INHIBITORS/VORAPAXAR
• STRONG & MODERATE CYP3A4 INHIBITORS/GUANFACINE
• STRONG OR MODERATE CYP3A4 INHIBITORS/SIMEPREVIR
• STRONG CYP3A4 INHIBITORS/MACITENTAN
• STRONG CYP3A4 INHIBITORS/QUETIAPINE
• P-GP AND STRONG CYP3A4 INHIBITORS/APIXABAN
• UGT INDUCERS/CANAGLIFLOZIN
• STRONG CYP3A4 INHIBITORS/MIFEPRISTONE
• STRONG AND MODERATE CYP3A4 INHIBITORS/IVACAFTOR
• SELECTED PROTEASE INHIBITORS/TELAPREVIR
• COBICISTAT; HCV OR HIV PROTEASE INHIBITORS/SALMETEROL
• STRONG UGT INDUCERS/DEFERASIROX
• DARUNAVIR; LOPINAVIR/VORICONAZOLE
• RITONAVIR/ULIPRISTAL
• PROTEASE INHIBITORS/BOSENTAN
• STRONG CYP3A4 INHIBITORS/EVEROLIMUS
• ATAZANAVIR; INDINAVIR; LOPINAVIR/PHENOBARBITAL; PHENYTOIN
• P-GLYCOPROTEIN (P-GP) INHIBITORS/TOPOTECAN
• CYP2D6 INHIBITORS/TAMOXIFEN
• SELECTED PROTEASE INHIBITORS/MARAVIROC
• LOPINAVIR; SAQUINAVIR; OMBITAS-PARITAP-RITONAVIR/DARUNAVIR
• PROTEASE INH;COBICISTAT/SLT IMMUNOSUPPRESSANTS;TEMSIROLIMUS
• STRONG 3A4 INHIBITORS/COLCHICINE
• SLT 3A4 INHIBIT/ALFENTANIL; FENTANYL; HYDROCODONE; OXYCODONE
• SELECTED CYP3A4 INHIBITORS/TRAZODONE
• SELECTED CYP3A4 INHIBITORS/SELECTED STEROIDS

Moderate Interactions of Kaletra Solution:

These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

• RITONAVIR/BUPROPION
• RITONAVIR/MEPERIDINE
• BOCEPREVIR; RITONAVIR; TELAPREVIR/ALPRAZOLAM
• SELECTED PROTEASE INHIBITORS/DIDANOSINE
• LOPINAVIR/EFAVIRENZ; NEVIRAPINE
• ATAZANAVIR; RITONAVIR/POSACONAZOLE
• LOPINAVIR/POSSIBLE QT PROLONGING AGENTS
• DARUNAVIR; LOPINAVIR; RITONAVIR/GLECAPREVIR-PIBRENTASVIR
• STRONG CYP3A4 INHIBITORS/MIDOSTAURIN
• RITONAVIR/LEVOTHYROXINE
• SELECTED CYP1A2 INDUCERS/OLANZAPINE
• LAPATINIB; RITONAVIR/EDOXABAN 60 MG
• LOPINAVIR; NELFINAVIR; NEVIRAPINE; RITONAVIR/WARFARIN DERIVS
• P-GP AND SELECTED CYP 3A4 INHIBITORS/NINTEDANIB
• STRONG 3A4 INHIB/LEVOMILNACIPRAN(<=80MG);VILAZODONE(<=20MG)
• P-GLYCOPROTEIN (P-GP) INHIBITORS/AFATINIB
• STRONG CYP1A2 OR CYP3A4 INHIBITORS/POMALIDOMIDE
• STRONG CYP3A4 INHIBITORS/REGORAFENIB
• NELFINAVIR; RITONAVIR; TELAPREVIR/METHADONE
• LOPINAVIR; RITONAVIR/LAMOTRIGINE
• STRONG CYP3A4 INHIBITORS/PANOBINOSTAT (=< 10 MG); ROMIDEPSIN
• HIV PROTEASE INHIBITORS;COBICISTAT/SILDENAFIL (ED);TADALAFIL
• RITONAVIR/ALMOTRIPTAN
• STRONG CYP3A4 INHIBITORS/SAXAGLIPTIN (=< 2.5 MG)
• ATAZANAVIR; LOPINAVIR; SIMEPREVIR/ROSUVASTATIN (<= 10 MG)
• SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/DABIGATRAN
• CYP3A4; CYP2C8; P-GLYCOPROTEIN (P-GP) INHIBITORS/LOPERAMIDE
• STRONG CYP3A4 INHIBITORS/BUSPIRONE
• LOPINAVIR/SELECTED PROTEASE INHIBITORS
• STRONG CYP3A4 INHIBITORS/ESZOPICLONE; ZOPICLONE; ZOLPIDEM
• SELECTED 3A4 INHIBITORS/ITRACONAZOLE; KETOCONAZOLE
• SELECTED PROTEASE INHIBITORS/SELECTED ANTIARRHYTHMICS
• SELECTED PROTEASE INHIBITORS; COBICISTAT/ATORVASTATIN
• STRONG CYP3A4 INHIB/ARIPIPRAZOLE; BREXPIPRAZOLE; ILOPERIDONE
• STRONG CYP3A4 INHIBITORS/ARTEMETHER;LUMEFANTRINE;MEFLOQUINE
• SELECTED PROTEASE INHIBITORS/CLARITHROMYCIN
• STRONG CYP3A4 INHIBITORS/SLT LOW STRENGTH ANTIMUSCARINICS