TRISENOX Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • low amount of magnesium in the blood
  • low amount of calcium in the blood
  • acidosis, a high level of acid in the blood
  • high levels of potassium in the blood
  • low amount of potassium in the blood
  • a type of blood clotting disorder called disseminated intravascular coagulation
  • decreased blood platelets
  • low levels of a type of white blood cell called neutrophils
  • high levels of white blood cells
  • high blood pressure
  • prolonged QT interval on EKG
  • bleeding
  • bleeding of the stomach or intestines
  • coma
  • seizures
  • trouble breathing
  • decreased urine production
  • high blood sugar

If experienced, these tend to have a Less Severe expression i

  • difficulty sleeping
  • fever
  • low energy
  • headache
  • cough
  • nausea
  • vomiting
  • diarrhea
  • intense abdominal pain
  • fast heartbeat

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • escape of fluid into the lungs
  • decreased kidney function
  • abnormal liver function tests

If experienced, these tend to have a Less Severe expression i

  • anemia
  • depression
  • blurred vision
  • eye pain
  • bruising under the skin
  • a sore throat
  • a common cold
  • inflammation of the tissue lining the sinuses
  • indigestion
  • constipation
  • bleeding not related to menstrual period
  • inflammation of the skin due to an allergy
  • itching
  • joint pain
  • neck pain
  • backache
  • pain in the arms or legs
  • bone pain
  • dizziness
  • excessive sweating
  • chills
  • muscle tremors
  • visible water retention
  • loss of skin color
  • temporary redness of face and neck
  • decreased appetite
  • nosebleed
  • heart throbbing or pounding
  • wheezing
  • chest pain
  • decreased oxygen in the tissues or blood
  • reactions at the site of the injection
  • a feeling of pins and needles on skin
  • anxious feelings

RARE side effects

If experienced, these tend to have a Severe expression i

  • shingles
  • malignant melanoma, a type of skin cancer
  • pancreatic adenocarcinoma, a cancer that forms in the glands of the pancreas
  • squamous cell carcinoma
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • a type of brain function problem called encephalopathy
  • hearing loss
  • atrioventricular block, a type of slow heart rhythm disorder
  • rapid ventricular heartbeat
  • torsades de pointes, a type of abnormal heart rhythm
  • ventricular premature beats
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a condition with muscle tissue breakdown called rhabdomyolysis
  • high amount of bilirubin in the blood
  • differentiation syndrome in acute promyelocytic leukemia
  • Wernicke's encephalopathy
  • a type of brain disorder called posterior reversible encephalopathy syndrome
  • a high aspartate transaminase level

If experienced, these tend to have a Less Severe expression i

  • thrush
  • confusion
  • agitation
  • a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
  • dry eye
  • ringing in the ears
  • an earache
  • dry mouth
  • muscle pain
  • puffy face from water retention
  • small reddish-purplish pin-point sized spots on skin
  • weight loss
  • swollen lymph nodes
  • rapid breathing
  • coughing up of blood
  • the inability to control a bowel movement
  • abdominal bloating
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.