What should I Know Regarding Pregnancy, Nursing and Administering Phenyleph-Pyril-DM-Acetaminoph Liquid to Children or the Elderly?

If you are PREGNANT

  • FDB Only When Necessary: AVAILABLE DATA SUGGEST NO KNOWN RISK; OTC PRODUCT, NO FDA PREGNANCY WARNINGS
  • Only When Necessary:
  • FDB Only When Necessary: NO FDA CATEGORY; INCR RISK OF RETROLENTAL FIBROPLASIA SEEN IN PREMATURE INFANTS
  • Only When Necessary: EVIDENCE FOR MALFORMATIONS; CAN REDUCE UTERINE BLOOD FLOW CAUSING FETAL HYPOXIA

If you are NURSING

  • No Known Risk: LOW LEVELS EXCRETED WITH LOW RISK FOR ADVERSE EFFECTS IN INFANT
  • Precaution: INSUFFICIENT DATA AVAILABLE; MOLECULAR WT LOW ENOUGH FOR POSSIBLE EXCRETION
  • Precaution: ORAL BIOAVAILABILITY LOW; INFANT EXPOSURE MAY BE MINIMAL
  • Precaution: USE IS NOT RECOMMENDED; MAY CAUSE UNUSUAL EXCITEMENT OR IRRITABILITY

If you are an adult over 60

  • management or monitoring precaution: Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
  • management or monitoring precaution: Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Non-sedating antihistamine preferred. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
  • management or monitoring precaution: Hepatic-Elderly may be more susceptible to hepatotoxicity. Strict adherence to a maximum daily dose is recommended, and the maximum dose recommendation varies between 3000-3800 mg depending on strength used and source of the recommendation.

Giving Phenyleph-Pyril-DM-Acetaminoph Liquid to a child under 12

  • management or monitoring precaution: Use weight based dosing in children less than 12 years.
  • Contraindication: Do not use in pediatrics <6 years of age unless clinician consultation.
  • Contraindication: Do not use in pediatrics <6 years of age unless clinician consultation.
  • Contraindication: Risk of CNS excitation. Do not use age <6 years without clinician consult.
  • Contraindication: Possible CNS excitation and seizure risk in newborns.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.