Promethazine-codeine Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • low blood pressure
  • fast heartbeat
  • If experienced, these tend to have a Less Severe expression i

  • constipation
  • drowsiness
  • inducing of a relaxed easy state
  • excessive sweating
  • nausea
  • vomiting
  • stomach cramps
  • confusion
  • over excitement
  • nightmares
  • blurred vision
  • a change in vision
  • ringing in the ears
  • an increase in the thickness of lung secretions
  • dry mouth
  • increased sensitivity of the skin to the sun
  • dizziness
  • a skin rash
  • nervousness
  • irritability
  • INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

  • orthostatic hypotension, a form of low blood pressure
  • low blood pressure
  • a complete or partial collapse of the lung airways called atelectasis
  • decreased lung function
  • trouble breathing
  • abnormal nervous system function affecting alertness
  • inducing of a relaxed easy state
  • If experienced, these tend to have a Less Severe expression i

  • a change in vision
  • dry mouth
  • fainting
  • dizziness
  • decreased appetite
  • headache
  • heart throbbing or pounding
  • decreased urine production
  • nervousness
  • generalized weakness
  • feelings of dissatisfaction, sadness, and unease
  • stuffy nose
  • excessive sweating
  • RARE side effects

    If experienced, these tend to have a Severe expression i

  • decreased function of the adrenal gland
  • deficiency of a substance that promotes masculinization
  • dependence on opioid-type drugs
  • addiction to a drug
  • complete stoppage of the heart
  • slow heartbeat
  • lung failure causing loss of breath
  • blocked bowels with decreased peristaltic movement
  • seizures
  • sleep apnea
  • a condition where the body is unable to maintain adequate blood flow called shock
  • a significant type of allergic reaction called anaphylaxis
  • accidental falls
  • pancreatitis
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • dissociation
  • extrapyramidal disease, a type of movement disorder
  • neuroleptic malignant syndrome, a reaction characterized by fever, muscle rigidity and confusion
  • high blood pressure
  • prolonged QT interval on EKG
  • thrombotic thrombocytopenic purpura, a type of blood disorder
  • asthma
  • decreased lung function
  • a blockage of the bile duct that resulting in high bilirubin levels
  • hives
  • delirium
  • hallucinations
  • apnea, a breathing interruption
  • a type of allergic reaction called angioedema
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
  • If experienced, these tend to have a Less Severe expression i

  • an extreme sense of wellbeing called euphoria
  • depression
  • widening of blood vessels
  • irritation of the stomach or intestines
  • spasm of a bile duct tract
  • the inability to have an erection
  • sensation of spinning or whirling
  • difficulty sleeping
  • low energy
  • temporary redness of face and neck
  • diarrhea
  • anxious feelings
  • skin inflammation
  • muscle tremors
  • loss of muscle coordination
  • decreased appetite
  • nausea
  • vomiting
  • difficult or painful urination
  • Free RX Coupon

    Save up to 80% on your prescriptions.

    Available coupons

    Save up to 80% on your prescription with WebMDRx

    Drug Survey

    Are you currently using Promethazine-codeine?

    This survey is being conducted by the WebMD marketing sciences department.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.