Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • increase in the number of platelets in the blood

If experienced, these tend to have a Less Severe expression i

  • low levels of white blood cells
  • increased eosinophils in the blood
  • diarrhea

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • decreased blood platelets
  • a skin rash
  • a high alanine transaminase level
  • a high aspartate transaminase level
  • low blood pressure

If experienced, these tend to have a Less Severe expression i

  • abnormal liver function tests
  • reactions at the site of the injection
  • a fibrous thickening of the skin called induration
  • chills
  • headache

RARE side effects

If experienced, these tend to have a Severe expression i

  • diarrhea from an infection with Clostridium difficile bacteria
  • destruction of red blood cells by body's own antibodies
  • a decrease in the blood clotting protein prothrombin
  • increased risk of bleeding due to clotting disorder
  • very low levels of granulocytes, a type of white blood cell
  • low levels of a type of white blood cell called neutrophils
  • high levels of white blood cells
  • increased lymphocyte cells in the blood
  • a decreased number of lymphocytes in the blood
  • a type of brain function problem called encephalopathy
  • inflammation in the lungs due to an allergic reaction
  • bronchospasm
  • inflammation of the large intestine
  • inflammation of the liver called hepatitis
  • a stone in the common bile duct called choledocholithiasis
  • kidney stones
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • itching
  • seizures
  • a fever as a result of taking the medication
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • a serum sickness reaction
  • stones in the urinary tract
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
  • pancreatitis
  • a type of skin disorder called acute generalized exanthematous pustulosis
  • occlusion of the ureter due to calculus
  • a type of significant allergic skin reaction called DRESS syndrome
  • methemoglobinemia, a type of blood disorder
  • confusion
  • a toxic effect on the central nervous system, which consists of the brain and spinal cord
  • high blood pressure
  • slow heartbeat
  • abnormal heart rhythm
  • ventricular arrhythmias, a type of abnormal heart rhythm
  • depression of the function of the heart
  • widening of blood vessels
  • a prolonged asthma attack
  • decreased lung function
  • hives
  • drowsiness
  • unconsciousness
  • a skin rash
  • nausea
  • vomiting
  • damage to the bone cartilage in the joint
  • hemiparesis
  • fast heartbeat

If experienced, these tend to have a Less Severe expression i

  • a yeast infection of the vagina and vulva
  • anemia
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • a painful, red or swollen tongue
  • indigestion
  • bloody urine
  • dizziness
  • excessive sweating
  • chills
  • taste impairment
  • visible water retention
  • temporary redness of face and neck
  • headache
  • nosebleed
  • heart throbbing or pounding
  • nausea
  • vomiting
  • gas
  • decreased urine production
  • a condition where there is excess sugar in the urine
  • intense abdominal pain
  • inflammation of the vein, or phlebitis after infusion
  • apprehension
  • an extreme sense of wellbeing called euphoria
  • blurred vision
  • decreased pupil size
  • ringing in the ears
  • muscle tremors
  • muscle twitching
  • numbness
  • nervousness
  • a sensation of feeling warm
  • anxious feelings
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.