If you are:
Only When Necessary: NEONATAL WITHDRAWAL/RESP.DEPRESS. W/CHRONIC OR HIGH DOSE; SMALL TERATOGENIC RISK
Precaution: MONITOR FOR CHANGES IN RESPIRATION, GI EFFECTS, SEDATION, FEEDING PATTERNS
No Known Risk: LOW LEVELS EXCRETED WITH LOW RISK FOR ADVERSE EFFECTS IN INFANT
An adult over 60:
management or monitoring precaution: Pulmonary-Respiratory depression is more likely to occur in elderly, as they may have altered pharmacokinetics due to poor fat stores, muscle wasting, or altered clearance. Neuro/Psych-Risk for confusion, delirium and falls. Avoid treatment with 3 or more CNS active agents. Gastrointestinal-Constipation risk. Renal-Impaired function may lead to increased toxicity due to accumulation of parent compound and metabolites. Cardiovascular-Monitor for hypotension with high doses.
management or monitoring precaution: Hepatic-Elderly are more susceptible to hepatotoxicity. Strict adherence to a maximum daily dose of 3000mg is advised.
Giving Co-Gesic tablet to a child under 12:
management or monitoring precaution: Use weight based dosing in children less than 12 years.
Severe Precaution: Risk of respiratory depression. Safety and efficacy not established as cough suppressant age < 6 years.
Severe Precaution: Risk of respiratory depression. Caution with use. Weigh risk:benefit.