If you are:
FDB Contraindicated or Not Recommended: FDA C; RISK OF CV DEFECTS &ORAL CLEFT;FOLIC ACID SUPPLEMENTATION MAY REDUCE RISK
No Known Risk: NO REPORTED ADVERSE EFFECTS ON 50 INFANTS.
An adult over 60:
management or monitoring precaution: Renal-Rare risk of hyperkalemia. May need to monitor potassium and renal function. Dose adjust for CrCL < 31 mL/minute.
Giving trimethoprim to a child under 12:
management or monitoring precaution: Effectiveness of trimethoprim as single agent has not been established for age <12 years. Safety and efficacy not established age < 2 months.