LAMOTRIGINE Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • fever
  • a skin rash

If experienced, these tend to have a Less Severe expression i

  • an infection
  • double vision
  • blurred vision
  • throat irritation
  • a stuffy and runny nose
  • dry mouth
  • backache
  • drowsiness
  • dizziness
  • difficulty sleeping
  • low energy
  • muscle tremors
  • headache
  • chest pain
  • nausea
  • vomiting
  • intense abdominal pain

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • bleeding
  • mental status changes
  • irritability
  • an accidental injury

If experienced, these tend to have a Less Severe expression i

  • mood changes
  • a change in vision
  • nystagmus, a condition with involuntary eye movements
  • indigestion
  • constipation
  • inflammation or infection of the vagina
  • pain with menstruation
  • joint pain
  • neck pain
  • pain
  • decreased appetite
  • weight loss
  • diarrhea
  • anxious feelings

RARE side effects

If experienced, these tend to have a Severe expression i

  • meningitis not due to an infection
  • a breast tumor
  • a reduction in the body's resistance to infection
  • a type of blood disorder where the red blood cells burst called hemolytic anemia
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • low blood counts due to bone marrow failure
  • anemia
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • increased eosinophils in the blood
  • a blood disorder
  • suicidal behavior
  • suicidal thoughts
  • repeated seizures with unconsciousness between episodes
  • inflammation of the uvea of the eye
  • hearing loss
  • high blood pressure
  • ST segment changes on an EKG
  • ventricular arrhythmias, a type of abnormal heart rhythm
  • inflammation of the blood vessels
  • orthostatic hypotension, a form of low blood pressure
  • inflammation of the esophagus
  • inflammation of the large intestine with bleeding
  • bleeding of the stomach or intestines
  • a type of kidney inflammation called interstitial nephritis
  • acute kidney failure
  • inflammation of the epididymis of the testicles
  • an acute skin rash
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • skin rash with sloughing
  • a condition with symptoms that resemble lupus
  • a condition with muscle tissue breakdown called rhabdomyolysis
  • a type of abnormal movement disorder called dyskinesia
  • high amount of bilirubin in the blood
  • small reddish-purplish pin-point sized spots on skin
  • swelling of the tongue
  • apnea, a breathing interruption
  • abnormal liver function tests
  • a type of allergic reaction called angioedema
  • a hypersensitivity reaction to a drug
  • defect in heart's electrical intraventricular conduction
  • problems metabolizing alcohol
  • a type of immune system problem called hypogammaglobulinemia
  • pancreatitis
  • multiple organ failure
  • a type of significant allergic skin reaction called DRESS syndrome
  • hemophagocytic lymphohistiocytosis, a condition where the body makes too many activated immune cells
  • pure red cell aplasia
  • a high alanine transaminase level
  • a high aspartate transaminase level

If experienced, these tend to have a Less Severe expression i

  • a goiter
  • panic disorder
  • aggressive behavior
  • feelings of hostility
  • hyperactive behavior
  • lazy eye
  • visual sensitivity to light
  • drooping of the upper eyelid
  • dry eye
  • ringing in the ears
  • an earache
  • bruising under the skin
  • widening of blood vessels
  • inflammation of the tissue lining the sinuses
  • inflammation of the gums
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • canker sores
  • a painful, red or swollen tongue
  • a type of stomach irritation called gastritis
  • inflammation of the bladder
  • breastmilk production not associated with childbirth or nursing
  • erythema or redness of skin or mucous membrane
  • itching
  • hair loss
  • hirsutism, a condition of hair growth on parts of the body normally without hair
  • acne
  • skin discoloration
  • decreased pigmentation of the skin
  • arthritis
  • inflammation of the sac surrounding the joint - bursitis
  • muscle weakness
  • leg cramps
  • memory loss
  • hallucinations
  • fainting
  • a sleep disorder
  • chills
  • muscle twitching
  • taste impairment
  • a distorted sense of smell called parosmia
  • temporary redness of face and neck
  • increased hunger
  • a type of speech disorder called dysarthria
  • heart throbbing or pounding
  • swollen lymph nodes
  • rapid deep breathing
  • yawning
  • hiccups
  • difficulty swallowing
  • burping
  • difficult or painful urination
  • an inability to completely empty the bladder
  • urination during the night
  • high blood sugar
  • a feeling of pins and needles on skin
  • urinary urgency, or the sudden urge to urinate
  • generalized weakness
  • a feeling of general discomfort called malaise
  • a type of bumpy skin rash called a maculopapular rash
  • orgasm problems
  • muscle wasting
  • a loss of taste
  • drug-induced hot flashes
  • fast heartbeat

Free RX Coupon

Save up to 80% on your prescriptions.

Available coupons

Save up to 80% on your prescription with WebMDRx

You Might Also Like

Drug Survey

Are you currently using lamotrigine?

This survey is being conducted by the WebMD marketing sciences department.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.