Isosorbide Dinitrate

COMMON BRAND(S): Isordil

GENERIC NAME(S): Isosorbide Dinitrate

Uses

Uses

Isosorbide dinitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). This medication belongs to a class of drugs known as nitrates. It works by relaxing and widening blood vessels so blood can flow more easily to the heart.

This medication will not relieve chest pain once it occurs. It is also not intended to be taken just before physical activities (such as exercise, sexual activity) to prevent chest pain. Other medications may be needed in these situations. Consult your doctor for more details.

How to use Isosorbide Dinitrate

Take this medication by mouth, usually 2 to 3 times daily or as directed by your doctor. It is important to take the drug at the same times each day. Do not change the dosing times unless directed by your doctor.

Use this medication regularly to get the most benefit from it. Do not suddenly stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.

Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. Tell your doctor if this medication stops working well (for example, you have worsening chest pain or it occurs more often).

Side Effects

Side Effects

Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Headache is often a sign that this medication is working. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). If the headaches continue or become severe, tell your doctor promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: fainting, fast/irregular/pounding heartbeat.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Precautions

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as isosorbide mononitrate, nitroglycerin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: recent head injury.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: anemia, low blood pressure, loss of too much body water (dehydration), other heart problems (such as recent heart attack).

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before having surgery, tell your doctor or dentist that you are using this medication.

Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk or if it may harm a nursing infant. Consult your doctor before breast-feeding.

Interactions

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), certain drugs to treat migraine headaches (ergot alkaloids such as ergotamine), riociguat.

Some products have ingredients that could worsen your heart failure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).

Isosorbide dinitrate is very similar to isosorbide mononitrate. Do not use medications containing isosorbide mononitrate while using isosorbide dinitrate.

This medication may interfere with certain laboratory tests (including blood cholesterol levels), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Overdose

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips.

Notes

Do not share this medication with others.

Laboratory and/or medical tests (such as blood pressure monitoring) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Lifestyle changes such as dietary changes, exercise, and stopping smoking may help this drug work better. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is within 2 hours of the next dose, skip themissed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.Information last revised June 2017. Copyright(c) 2017 First Databank, Inc.

Images
isosorbide dinitrate 20 mg tablet
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isosorbide dinitrate 20 mg tablet

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isosorbide dinitrate 10 mg tablet
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isosorbide dinitrate 5 mg tablet
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isosorbide dinitrate 5 mg tablet

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isosorbide dinitrate 10 mg tablet
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isosorbide dinitrate 10 mg tablet

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isosorbide dinitrate 5 mg tablet
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isosorbide dinitrate 5 mg tablet

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isosorbide dinitrate 20 mg tablet
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isosorbide dinitrate 20 mg tablet

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isosorbide dinitrate 30 mg tablet
isosorbide dinitrate 30 mg tableticonicon
isosorbide dinitrate 30 mg tablet

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par 009
isosorbide dinitrate 5 mg tablet
isosorbide dinitrate 5 mg tableticonicon
isosorbide dinitrate 5 mg tablet

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par 020
isosorbide dinitrate 10 mg tablet
isosorbide dinitrate 10 mg tableticonicon
isosorbide dinitrate 10 mg tablet

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par 021
isosorbide dinitrate 20 mg tablet
isosorbide dinitrate 20 mg tableticonicon
isosorbide dinitrate 20 mg tablet

color
green
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par 022
isosorbide dinitrate 20 mg tablet
isosorbide dinitrate 20 mg tablet

color
green
shape
round
imprint
W W, 772
This medicine is a green, round, scored, tablet imprinted with "W W" and "772".
isosorbide dinitrate 10 mg tablet
isosorbide dinitrate 10 mg tablet

color
white
shape
round
imprint
W W, 771
This medicine is a white, round, scored, tablet imprinted with "W W" and "771".
isosorbide dinitrate 5 mg tablet
isosorbide dinitrate 5 mg tablet

color
white
shape
round
imprint
West-ward 769
This medicine is a white, round, scored, tablet imprinted with "West-ward 769".
isosorbide dinitrate 10 mg tablet
isosorbide dinitrate 10 mg tablet

color
white
shape
round
imprint
GG 26
This medicine is a white, round, scored, tablet imprinted with "GG 26".
isosorbide dinitrate 5 mg tablet
isosorbide dinitrate 5 mg tablet

color
pink
shape
round
imprint
GG 259
This medicine is a pink, round, scored, tablet imprinted with "GG 259".
isosorbide dinitrate 20 mg tablet
isosorbide dinitrate 20 mg tablet

color
green
shape
round
imprint
GG 227
This medicine is a green, round, scored, tablet imprinted with "GG 227".
isosorbide dinitrate 30 mg tablet
isosorbide dinitrate 30 mg tablet

color
blue
shape
round
imprint
par 009
This medicine is a blue, round, scored, tablet imprinted with "par 009".
isosorbide dinitrate 5 mg tablet
isosorbide dinitrate 5 mg tablet

color
white
shape
round
imprint
par 020
This medicine is a white, round, scored, tablet imprinted with "par 020".
isosorbide dinitrate 10 mg tablet
isosorbide dinitrate 10 mg tablet

color
white
shape
round
imprint
par 021
This medicine is a white, round, scored, tablet imprinted with "par 021".
isosorbide dinitrate 20 mg tablet
isosorbide dinitrate 20 mg tablet

color
green
shape
round
imprint
par 022
This medicine is a green, round, scored, tablet imprinted with "par 022".

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.