Ivabradine/Moderate CYP3A4 Inhibitors that Prolong QT Interactions
How the interaction occurs:
Some medicines may slow down how quickly your liver processes ivabradine and may cause your heart to slow down too much.
What might happen:
The amount of ivabradine in your blood may increase and cause your heart to slow down too much, which may be life-threatening.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know right away that you are using these medicines together. Your doctor may want to change your medicine. Let your healthcare professionals know if your heart rate slows below 50 beats per minute or if you have any dizziness, fatigue, or other symptoms of low blood pressure such as fainting or lightheadedness. Let your doctor know if you experience a racing heart, chest pressure, or worsening shortness of breath.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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