HMG-CoA Reductase Inhibitors/Niacin (Greater Than or Equal To 250 mg) Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
The cause of the interaction is not known.
What might happen:
When the two medicines are taken together, you may experience muscle aches, tenderness, and weakness.
What you should do about this interaction:
Contact your healthcare professionals (e.g. doctor or pharmacist) as soon as possible about taking these two medicines together. They may already be aware of this interaction and may be monitoring you for it. If your doctor prescribes these medicines together, report any symptoms of muscle aches, tenderness, weakness, changes in the color of your urine, or flu-like symptoms. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Mevacor (lovastatin) US prescribing information. Merck & Co., Inc. February, 2014.
- 2.Niaspan (niacin) US prescribing information. Abbott Laboratories February, 2013.
- 3.Lipitor (atorvastatin) US prescribing information. Pfizer Inc. November, 2019.
- 4.Livalo (pitavastatin) US prescribing information. Kowa Pharmaceuticals America, Inc. May, 2019.
- 5.Crestor (rosuvastatin calcium) US prescribing information. AstraZeneca Pharmaceuticals LP May, 2020.
- 6.Zocor (simvastatin) US prescribing information. Merck & Co., Inc. October, 2019.
- 7.Vytorin (ezetimibe/simvastatin) US prescribing information. Merck/Schering-Plough Pharmaceuticals October, 2019.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.