What should I Know Regarding Pregnancy, Nursing and Administering Clozaril to Children or the Elderly?
If you are PREGNANT
- Possibly Safe: NON-TERATOGENIC COMPLICATIONS (RESP, GI,CNS) WITH EXPOSURE DURING 3RD TRIMESTER
If you are NURSING
- Absolute Contraindication: NOT RECOMMENDED: POSSIBLE SEVERE HEMATOLOGIC ADVERSE EFFECTS.
If you are an adult over 60
- management or monitoring precaution: Neuro/Psych-Generally not recommended. Higher risk of tardive dyskinesia. May cause sedation, worsen cognitive impairment and increase fall risk. Increased risk of death in senile dementia. Cardiovascular-Risk of orthostatic hypotension and tachycardia. Cardiovascular and cerebrovascular risks may increase with hyperglycemia, lipid changes, weight gain. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention.
Giving Clozaril to a child under 12
- management or monitoring precaution: Risk of severe neutropenia, seizure, cardiomyopathy, orthostatic hypotension, respiratory arrest. Safety and efficacy not established.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.