Does PACERONE Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED ANTIARRHYTHMICS/QUINIDINE
  • SELECTED ANTIARRHYTHMICS/SAQUINAVIR
  • CYP3A4 SUBSTRATES THAT PROLONG QT/POSACONAZOLE
  • QT PROLONGING AGENTS/LEVOKETOCONAZOLE
  • QT PROLONGING AGENTS/HYDROXYCHLOROQUINE
  • WEAK CYP3A4 INHIBITORS/LOMITAPIDE (>40MG)
  • SELECTED CLASS I & CLASS III ANTIARRHYTHMIC AGENTS/SOTALOL
  • QT PROLONGING AGENTS/ANAGRELIDE
  • CLASS IA AND III ANTIARRHYTHMIC AGENTS/FINGOLIMOD
  • QT PROLONGING AGENTS/DOMPERIDONE
  • AMIODARONE/LOVASTATIN (> 40 MG); SIMVASTATIN (> 20 MG)
  • QT PROLONGING AGENTS/DRONEDARONE
  • QT PROLONGING AGENTS/ARTEMETHER-LUMEFANTRINE
  • CLASS IA AND III ANTIARRHYTHMICS/DISOPYRAMIDE
  • CLASS IA AND III ANTIARRHYTHMICS/IBUTILIDE
  • SELECTED CLASS IA AND III ANTIARRHYTHMICS/PROPAFENONE
  • QT PROLONGING AGENTS/SERTINDOLE
  • QT PROLONGING AGENTS/DROPERIDOL
  • QT PROLONGING AGENTS/LEVOMETHADYL
  • SELECTED QT PROLONGING AGENTS/ZIPRASIDONE
  • QT PROLONGING AGENTS/BEPRIDIL
  • CLASS IA AND CLASS III ANTIARRHYTHMICS/DOFETILIDE
  • SELECTED CLASS IA & III ANTIARRHYTHMICS/CISAPRIDE
  • SELECTED CLASS I & III ANTIARRHYTHMICS/MIZOLASTINE
  • SELECTED ANTIARRHYTHMICS/PIMOZIDE
  • CLASS I AND III ANTIARRHYTHMICS/HALOFANTRINE
  • SELECTED AGENTS/MIBEFRADIL
  • CLASS IA & III ANTIARRHYTHMICS/SELECTED QUINOLONES
  • AMIODARONE/SELECTED PROTEASE INHIBITORS
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • AMIODARONE/COUMARIN ANTICOAGULANTS
  • AMIODARONE; DRONEDARONE/DIGITALIS GLYCOSIDES
  • AMIODARONE/DILTIAZEM; VERAPAMIL
  • SELECTED ANTIARRHYTHMICS/QUINUPRISTIN-DALFOPRISTIN
  • AMIODARONE/QT PROLONGING AGENTS
  • AMIODARONE; DRONEDARONE/RIFAMPIN; RIFAPENTINE
  • AMIODARONE/SELECTED STRONG CYP3A4 INDUCERS
  • AMIODARONE; DRONEDARONE/ST. JOHN'S WORT
  • SELECTED ANTIARRHYTHMICS/ELVITEGRAVIR-COBICISTAT
  • AMIODARONE/SOFOSBUVIR + SELECTED DIRECT ACTING ANTIVIRALS
  • AMIODARONE/VORICONAZOLE
  • QT PROLONGING AGENTS/PACRITINIB
  • QT PROLONGING AGENTS/PANOBINOSTAT
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/BILASTINE
  • DUAL WEAK CYP2D6 AND CYP3A4 INHIBITORS/ELIGLUSTAT
  • SELECTED QT PROLONGING AGENTS/INTRAVENOUS LEFAMULIN
  • QT PROLONGING AGENTS/MOBOCERTINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/DOXORUBICIN
  • SELECT MODERATE CYP2C9 INHIBITORS THAT PROLONG QT/SIPONIMOD
  • P-GP INHIBITORS/RIMEGEPANT
  • QT PROLONGING AGENTS/FEXINIDAZOLE
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/RELUGOLIX
  • WEAK CYP3A4 INHIBITORS/LONAFARNIB
  • QT PROLONGING AGENTS/LEVOMEPROMAZINE
  • QT PROLONGING AGENTS/SELPERCATINIB
  • QT PROLONGING AGENTS/OXALIPLATIN
  • P-GP OR BCRP INHIBITORS THAT PROLONG QT/PAZOPANIB
  • P-GP INHIBITORS THAT PROLONG QT/ORAL LEFAMULIN
  • QT PROLONGING AGENTS/ENTRECTINIB
  • QT PROLONGING AGENTS/GLASDEGIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/TALAZOPARIB
  • QT PROLONGING AGENTS/IVOSIDENIB
  • QT PROLONGING AGENTS/ENCORAFENIB
  • QT PROLONGING AGENTS/LOFEXIDINE
  • QT PROLONGING AGENTS/MACIMORELIN
  • STRONG AND MODERATE CYP2C9 INHIBITORS/BOSENTAN
  • QT PROLONGING AGENTS/INOTUZUMAB OZOGAMICIN
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/BETRIXABAN
  • QT PROLONGING AGENTS/RIBOCICLIB
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/VENETOCLAX
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/COLCHICINE
  • QT PROLONGING AGENTS/HYDROXYZINE
  • QT PROLONGING AGENTS/PIMAVANSERIN
  • WEAK CYP3A4 INHIBITORS/LOMITAPIDE (>30MG OR <=40MG)
  • QT PROLONGING AGENTS/GADOFOSVESET
  • QT PROLONGING AGENTS/OSIMERTINIB
  • SELECTED CLASS IA & III ANTIARRHYTHMICS/SELECTED QUINOLONES
  • QT PROLONGING AGENTS/TRAZODONE (>= 100 MG)
  • CLASS I & CLASS III ANTIARRHYTHMICS/VERNAKALANT
  • CLASS IA & III ANTIARRHYTHMICS/BUPRENORPHINE
  • AGENTS THAT AFFECT IODIDE/RADIOACTIVE IODIDE
  • QT PROLONGING AGENTS/QUININE
  • QT PROLONGING AGENTS/TOREMIFENE
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/TOPOTECAN
  • QT PROLONGING AGENTS/ZUCLOPENTHIXOL
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/DABIGATRAN
  • SELECTED ANTIARRHYTHMICS/TIZANIDINE
  • QT PROLONGING AGENTS/IVABRADINE
  • AMIODARONE; AJMALINE; QUINIDINE/ATAZANAVIR
  • AMIODARONE/AGALSIDASE
  • QT PROLONGING AGENTS/MESORIDAZINE
  • QT PROLONGING AGENTS/THIORIDAZINE
  • AMIODARONE/PROCAINAMIDE
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED ANTIARRHYTHMICS/SELECTED PROTEASE INHIBITORS
  • AMIODARONE/FENTANYL
  • AMIODARONE/POSSIBLE QT PROLONGING AGENTS
  • QT PROLONGING AGENTS/TRICLABENDAZOLE
  • QT PROLONGING AGENTS/OZANIMOD
  • QT PROLONGING AGENTS/PONESIMOD
  • QT PROLONGING AGENTS/GALANTAMINE
  • SELECTED WEAK CYP2D6 INHIBITORS/TAMOXIFEN
  • QT PROLONGING AGENTS/OSILODROSTAT
  • QT PROLONGING AGENTS/AMISULPRIDE
  • WEAK CYP3A4 INHIBITORS/UBROGEPANT
  • WEAK CYP3A4 INHIBITORS/LEMBOREXANT
  • MODERATE & WEAK CYP3A4 INHIBITORS THAT PROLONG QT/TACROLIMUS
  • QT PROLONGING AGENTS/PITOLISANT
  • SODIUM CHANNEL BLOCKER; POTASSIUM CHANNEL BLOCKER/LACOSAMIDE
  • QT PROLONGING AGENTS/GILTERITINIB
  • SELECT P-GP INHIBITORS/EDOXABAN (<= 30 MG)
  • QT PROLONGING AGENTS/TRAZODONE (< 100 MG)
  • AMIODARONE/LETERMOVIR
  • QT PROLONGING AGENTS/EFAVIRENZ
  • MODERATE CYP2C9 INHIBITORS/LESINURAD
  • SELECT P-GP INHIBITORS/EDOXABAN (> 30 MG)
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/AFATINIB
  • WEAK CYP3A4 INHIBITORS/LOMITAPIDE (<=30MG)
  • AMIODARONE; DRONEDARONE/SIROLIMUS
  • SELECTED P-GP AND WEAK CYP3A4 INHIBITORS/RIVAROXABAN
  • MODERATE CYP3A4; P-GP INHIBITORS/EVEROLIMUS
  • CLASS IA & III ANTIARRHYTHMICS/SUNITINIB
  • CLASS IA & III ANTIARRHYTHMICS/TOLTERODINE
  • CYP3A4; CYP2C8; P-GLYCOPROTEIN (P-GP) INHIBITORS/LOPERAMIDE
  • AMIODARONE/ATORVA; LOVA (<=40MG); SIMVASTATIN (<=20MG)
  • AMIODARONE; DRONEDARONE/SELECTED BETA-BLOCKERS
  • SELECTED CYP2C9 INHIBITORS/SELECTED NSAIDS
  • AMIODARONE/CYCLOSPORINE
  • AMIODARONE/SELECTED HYDANTOINS
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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.