Does VERAPAMIL HCL Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • STRONG AND MODERATE CYP3A4 INHIBITORS/LONAFARNIB
  • SLT STRONG & MODERATE CYP3A4 INHIBITORS/CILOSTAZOL (>50MG)
  • CLASS IB, II, AND IV ANTIARRHYTHMICS/DISOPYRAMIDE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/ASUNAPREVIR
  • STRONG OR MODERATE CYP3A4 INHIBITORS/LOMITAPIDE
  • MODERATE CYP3A4 INHIBITORS/NALOXEGOL (> 12.5 MG)
  • MODERATE CYP3A4 INHIBITORS/RANOLAZINE (> 500 MG BID)
  • MODERATE CYP3A4 INHIBITORS/AVANAFIL (> 50 MG)
  • STRONG OR MODERATE CYP3A4 INHIBITORS/FLIBANSERIN
  • DILTIAZEM; VERAPAMIL/LURASIDONE (> 80 MG)
  • VERAPAMIL/LOVASTATIN (> 20 MG); SIMVASTATIN (> 10 MG)
  • SELECTED CYP3A4 INHIBITORS/VARDENAFIL (> 5 MG)
  • VERAPAMIL/DOFETILIDE
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED CALCIUM CHANNEL BLOCKERS/RIFAMYCINS
  • SLT SENSITIVE 3A4 SUBSTRATES THAT INHIBIT 3A4/ORAL LEFAMULIN
  • MODERATE CYP3A4 INHIBITORS/PACRITINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/BILASTINE
  • MODERATE CYP3A4 INHIBITORS/MOBOCERTINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/DOXORUBICIN
  • P-GP INHIBITORS/RIMEGEPANT
  • STRONG AND MODERATE CYP3A4 INHIBITORS/FEXINIDAZOLE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/INFIGRATINIB
  • SELECTED MODERATE CYP3A4 INHIBITORS/ALPRAZOLAM
  • AGENTS THAT CAUSE BRADYCARDIA/PONESIMOD
  • MODERATE CYP3A4 INHIBITORS/VOCLOSPORIN
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/RELUGOLIX
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LURBINECTEDIN
  • MODERATE CYP3A4 INHIBITORS/SELPERCATINIB
  • MODERATE CYP3A4 INHIBITORS/PEXIDARTINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/PEMIGATINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/SELUMETINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LUMATEPERONE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LEMBOREXANT
  • MODERATE CYP3A4 INHIBITORS/ELEXACAFTOR-TEZACAFTOR-IVACAFTOR
  • MODERATE CYP3A4 INHIBITORS/ENTRECTINIB
  • AGENTS THAT CAUSE BRADYCARDIA/CRIZOTINIB
  • AGENTS THAT CAUSE BRADYCARDIA/SIPONIMOD
  • MODERATE CYP3A4 INHIBITORS/BRIGATINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/TALAZOPARIB
  • WEAK CYP2D6 INHIBITORS/ELIGLUSTAT
  • CLARITHROMYCIN; ERYTHROMYCIN; VERAPAMIL/RIVAROXABAN
  • STRONG AND MODERATE CYP3A4 INHIBITORS/ENCORAFENIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/TEZACAFTOR-IVACAFTOR
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/BETRIXABAN
  • STRONG CYP3A4 INHIB;MODERATE 3A4 & P-GP DUAL INHIB/NERATINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/DEFLAZACORT
  • MODERATE CYP3A4 INHIBITORS/VENETOCLAX
  • SELECTED INHIBITORS OF P-GP OR BCRP/PAZOPANIB
  • MODERATE CYP3A4 INHIBITORS/NALOXEGOL (<= 12.5 MG)
  • MODERATE CYP3A4 INHIBITORS/COBIMETINIB; OLAPARIB; SONIDEGIB
  • STRONG & MODERATE CYP3A4 INHIBITORS/ELIGLUSTAT
  • MODERATE CYP3A4 INHIBITORS/SUVOREXANT (> 10 MG)
  • MODERATE CYP3A4 INHIBITORS/ERGOT ALKALOIDS
  • SELECTED MODERATE CYP3A4 INHIBITORS/PIMOZIDE
  • STRONG & MODERATE CYP3A4 INHIBITORS/GUANFACINE
  • STRONG OR MODERATE CYP3A4 INHIBITORS/SIMEPREVIR
  • STRONG AND MODERATE CYP3A4 INHIBITORS/BOSENTAN
  • MODERATE CYP3A4 INHIBITORS/BOSUTINIB
  • BETA-BLOCKERS; AV NODE BLOCKERS/FINGOLIMOD
  • STRONG AND MODERATE CYP3A4 INHIBITORS/IVACAFTOR
  • FLECAINIDE; QUINIDINE; VERAPAMIL/DOLASETRON
  • MODERATE CYP3A4 INHIBITORS/COLCHICINE
  • MODERATE CYP3A4 INHIBITORS/TOLVAPTAN
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/TOPOTECAN
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/DABIGATRAN
  • DILTIAZEM; VERAPAMIL/MIDAZOLAM; TRIAZOLAM
  • SELECTED ANTIARRHYTHMICS/TIZANIDINE
  • CALCIUM CHANNEL BLOCKERS/DANTROLENE
  • MODERATE CYP3A4 INHIBITORS/IVABRADINE
  • SELECTED CALCIUM CHANNEL BLOCKERS/SELECTED MACROLIDES
  • SELECTED MODERATE CYP3A4 INHIBITORS/EPLERENONE
  • DILTIAZEM; VERAPAMIL/AMIODARONE
  • VERAPAMIL/NEUROMUSCULAR BLOCKING AGENTS
  • VERAPAMIL; MIBEFRADIL/DIGOXIN
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • CALCIUM CHANNEL BLOCKERS/QUINIDINE
  • DILTIAZEM; VERAPAMIL/ST. JOHN'S WORT
  • SELECTED CALCIUM CHANNEL BLOCKERS/SELECTED AZOLE ANTIFUNGALS
  • CALCIUM CHANNEL BLOCKERS/SELECTED HEPATITIS C AGENTS
  • SELECTED CALCIUM CHANNEL BLOCKERS/NIRMATRELVIR-RITONAVIR
  • MODERATE CYP3A4 INHIBITORS/MITAPIVAT
  • MODERATE CYP3A4 INHIBITORS/DARIDOREXANT
  • MODERATE CYP3A4 INHIBITORS/TAZEMETOSTAT
  • MODERATE CYP3A4 INHIBITORS/AVAPRITINIB
  • MODERATE CYP3A4 INHIBITORS/UBROGEPANT
  • MODERATE CYP3A4 INHIBITORS/ZANUBRUTINIB
  • SELECTED ANTIHYPERTENSIVES AND VASODILATORS/APOMORPHINE
  • MODERATE CYP3A4 INHIBITORS/ABEMACICLIB
  • BETA-BLOCKERS; CALCIUM CHANNEL BLOCKERS/LACOSAMIDE
  • SELECTED MODERATE CYP3A4 INHIBITORS/IVOSIDENIB
  • SELECT P-GP INHIBITORS/EDOXABAN (<= 30 MG)
  • MODERATE CYP3A4 INHIBITORS/CABERGOLINE
  • SELECTED MODERATE CYP3A4 INHIBITORS/ACALABRUTINIB
  • SELECTED ANTIHYPERTENSIVE AGENTS/SELECTED MAOIS
  • MODERATE CYP3A4 INHIBITORS/QUETIAPINE
  • MODERATE CYP3A4 INHIBITORS/BROMOCRIPTINE
  • SELECT P-GP INHIBITORS/EDOXABAN (> 30 MG)
  • MODERATE CYP3A4 INHIBITORS/BREXPIPRAZOLE
  • P-GP AND MODERATE CYP3A4 INHIBITORS/APIXABAN
  • P-GP AND SELECTED CYP3A4 INHIBITORS/NINTEDANIB
  • MODERATE CYP3A4 INHIBITORS/SUVOREXANT (<= 10 MG)
  • DILTIAZEM;DRONEDARONE;VERAPAMIL/TAMSULOSIN
  • MODERATE CYP3A4 INHIBITORS/AVANAFIL (<= 50 MG)
  • MODERATE CYP3A4 INHIBITORS/IBRUTINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/AFATINIB
  • SELECTED CYP3A4 INHIBITORS/VARDENAFIL (<= 5 MG)
  • DILTIAZEM; VERAPAMIL/LURASIDONE (<= 80 MG)
  • SELECTED MODERATE CYP3A4 INHIBITORS/SELECTED OPIOIDS
  • VERAPAMIL/ATORVA; LOVA (<= 20 MG); SIMVASTATIN(<= 10 MG)
  • DILTIAZEM; NIFEDIPINE; VERAPAMIL/DRONEDARONE
  • SELECTED CALCIUM CHANNEL BLOCKERS/TACROLIMUS
  • MODERATE CYP3A4; P-GP INHIBITORS/EVEROLIMUS
  • DILTIAZEM; VERAPAMIL/BUSPIRONE
  • SELECTED WEAK CYP2D6 INHIBITORS/TAMOXIFEN
  • MODERATE CYP3A4 INHIBITORS/RANOLAZINE (<=500 MG BID)
  • CYP3A4; CYP2C8; P-GLYCOPROTEIN (P-GP) INHIBITORS/LOPERAMIDE
  • SELECTED CALCIUM CHANNEL BLOCKERS/SIROLIMUS;TEMSIROLIMUS
  • SLT STRONG & MODERATE CYP3A4 INHIBITORS/CILOSTAZOL (<=50MG)
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/ETOPOSIDE
  • VERAPAMIL/SELECTED ALPHA-1 BLOCKERS
  • CALCIUM CHANNEL BLOCKERS/CYCLOSPORINE
  • SELECTED CALCIUM CHANNEL BLOCKERS/CARBAMAZEPINE
  • SELECTED CALCIUM CHANNEL BLOCKERS/SELECTED BETA-BLOCKERS
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    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.