ACITRETIN Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • joint pain
  • spinal hyperostosis, a bone growth disorder affecting the vertebrae
  • an abnormal increase in muscle tone
  • muscle pain
  • headache
  • nausea
  • vomiting

If experienced, these tend to have a Less Severe expression i

  • high cholesterol and high triglycerides
  • inflammation of the skin of the eyelid
  • dry eye
  • increased wax in the ears
  • a stuffy and runny nose
  • dryness of the nose
  • inflammation of the gums
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • chapped lips
  • increased sensitivity of the skin to the sun
  • itching
  • hair loss
  • peeling of the skin of the hands
  • peeling of the skin of the feet
  • excessive thirst
  • abnormal liver function tests

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • visual sensitivity to light
  • a change in vision
  • accumulation of fluid in the tissues of the eyelid
  • excessive watery eyes
  • eye pain
  • red eyes
  • eye irritation
  • inflammation and infection of nail cuticle
  • chills
  • a feeling of pins and needles on skin

If experienced, these tend to have a Less Severe expression i

  • blurred vision
  • pink eye
  • inflammation of the eyelid
  • canker sores
  • constipation
  • a nail disorder
  • low energy
  • excessive sweating
  • nosebleed
  • diarrhea

RARE side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • large purple or brown skin blotches
  • suicidal thoughts
  • depression
  • pseudotumor cerebri, a condition with high fluid pressure in the brain
  • a disease with shrinking and weaker muscles called myopathy
  • clouding of the lens of the eye called cataracts
  • decreased vision at night
  • erosion of the cornea of the eye
  • inflammation of the external ear resembling eczema
  • a heart attack
  • a stroke
  • obstruction of a blood vessel by a blood clot
  • capillary leak syndrome, a condition where fluid leaks out of small blood vessels
  • throat irritation
  • laryngitis
  • inflammation of the liver called hepatitis
  • acute inflammation of the pancreas
  • nodular inflammatory skin lesions with production of pus
  • inflammation of the skin due to an allergy
  • skin rash with sloughing
  • a psoriasis-like skin eruption
  • a skin ulcer
  • a groove in the skin
  • flu-like symptoms
  • a type of allergic reaction called angioedema
  • vulvovaginitis, an inflammation or infection of the vagina and vulva
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice

If experienced, these tend to have a Less Severe expression i

  • a stye
  • hives
  • high blood sugar
  • hyperesthesia, an increased nerve sensitivity
  • reduced eyelash growth
  • anxious feelings

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.