Theophylline Derivatives/Lithium Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, theophylline and medicines related to theophylline, including caffeine, may increase the amount of lithium output in your urine. This may lead to a decrease in amount of lithium in your blood.
What might happen:
A decrease in the beneficial effects of lithium may occur.
What you should do about this interaction:
If you experience restlessness, tremors, loss of appetite, or other symptoms, contact your doctor. If you change the amount of caffeine you consume, contact your doctor. Your doctor may want to check the amount of lithium in your blood.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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