Does Interact with other Medications?
Severe Interactions
These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
- SYMPATHOMIMETICS (INDIRECT & MIXED ACTING)/MAOIS
- SELECTED CYP1A2 SUBSTRATES/VILOXAZINE
- UGT1A1 INDUCERS/CABOTEGRAVIR
- CYP3A4 & UGT1A1 INDUCERS/CABOTEGRAVIR-RILPIVIRINE
- STRONG AND MODERATE CYP3A4 INDUCERS/LONAFARNIB
- STRONG CYP3A4 INDUCERS/FOSTEMSAVIR
- STRONG CYP3A4 INDUCERS/TAMOXIFEN
- STRONG CYP3A4 INDUCERS/LORLATINIB
- CYP3A4 INDUCERS/DORAVIRINE
- SELECTED CYP3A4 INDUCERS/ATAZANAVIR-COBICISTAT
- SELECTED CYP3A4 INDUCERS/COBICISTAT-ELVITEGRAVIR
- STRONG CYP3A4 INDUCERS/ELBASVIR-GRAZOPREVIR
- STRONG CYP3A4 INDUCERS/DELAMANID
- SLT MODERATE-STRONG CYP3A4 INDUCERS/SLT HEPATITIS C AGENTS
- STRONG CYP3A4 & P-GP INDUCERS/DACLATASVIR
- P-GP INDUCERS; PHENOBARBITAL/SELECTED HEPATITIS C AGENTS
- PDE INHIBITORS/RIOCIGUAT
- STRONG CYP3A4 INDUCERS/ARTEMETHER; LUMEFANTRINE
- CYP3A4 INDUCERS/RILPIVIRINE
- CYP3A4 INDUCERS/BOCEPREVIR; COBICISTAT; TELAPREVIR
- STRONG CYP3A4 INDUCERS/LURASIDONE
- CARBAMAZEPINE; PHENOBARBITAL; PHENYTOIN/PRAZIQUANTEL
- STRONG CYP3A4 INDUCERS/RANOLAZINE
- SELECTED ANTICONVULSANTS/NIFEDIPINE; NIMODIPINE; NISOLDIPINE
- SEDATIVE HYPNOTICS; ALCOHOL/SODIUM OXYBATE
- SELECTED CYP3A4 INDUCERS/ISAVUCONAZONIUM; VORICONAZOLE
- SELECTED ANTICONVULSANTS/DELAVIRDINE; ETRAVIRINE
- XANTHINE DERIVATIVES/DIPYRIDAMOLE INJECTABLE
Serious Interactions
These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
- THEOPHYLLINE DERIVATIVES/CIMETIDINE
- SELECT INDIRECT-ACTING SYMPATHOMIMETICS/TRICYCLIC COMPOUNDS
- SELECTED ANTICONVULSANTS; BARBITURATES/CONTRACEPTIVES
- THEOPHYLLINES/SELECTED QUINOLONES
- THEOPHYLLINES/HALOTHANE
- THEOPHYLLINES/ALLOPURINOL
- THEOPHYLLINES/CARBAMAZEPINE
- THEOPHYLLINES/TACRINE
- THEOPHYLLINE/RIFAMYCINS
- SELECTED ANTICONVULSANTS/TELITHROMYCIN
- CARBAMAZEPINE;HYDANTOINS;PHENOBARBITAL/SLT AZOLE ANTIFUNGALS
- PHENOBARBITAL; PHENYTOIN/SELECTED PROTEASE INHIBITORS
- MIXED;INDIRECT SYMPATHOMIMETICS/SELECTED MAOIS
- SELECTED CYP1A2 SUBSTRATES/VEMURAFENIB
- THEOPHYLLINE;TIZANIDINE/DEFERASIROX
- SELECTED CYP1A2 SUBSTRATES/CAPMATINIB
- STRONG CYP3A4 INDUCERS/TEPOTINIB
- STRONG AND MODERATE CYP3A4 INDUCERS/VOCLOSPORIN
- PDE INHIBITORS/VERICIGUAT
- STRONG CYP3A4 INDUCERS/LUMACAFTOR-IVACAFTOR
- STRONG CYP3A4 INDUCERS/PRALSETINIB
- STRONG CYP3A4 INDUCERS/PLITIDEPSIN
- SELECTED UGT1A1 INDUCERS/RALTEGRAVIR
- STRONG AND MODERATE CYP3A4 INDUCERS/LURBINECTEDIN
- STRONG CYP3A4 INDUCERS/RIPRETINIB
- STRONG AND MODERATE CYP3A4 INDUCERS/SELPERCATINIB
- STRONG AND MODERATE CYP3A4 INDUCERS/CAPMATINIB
- UGT1A1 INDUCERS/SACITUZUMAB GOVITECAN
- STRONG CYP3A4 INDUCERS; MODERATE CYP2C8 INDUCERS/TUCATINIB
- STRONG AND MODERATE CYP3A4 INDUCERS/PEMIGATINIB
- STRONG AND MODERATE CYP3A4 INDUCERS/SELUMETINIB
- STRONG AND MODERATE CYP3A4 INDUCERS/RIMEGEPANT
- STRONG OR MODERATE CYP3A4 INDUCERS/TAZEMETOSTAT
- STRONG CYP3A4 INDUCERS/REGORAFENIB
- STRONG OR MODERATE CYP3A4 INDUCERS/AVAPRITINIB
- CYP3A4 INDUCERS/LUMATEPERONE
- STRONG OR MODERATE CYP3A4 INDUCERS/LEMBOREXANT
- STRONG CYP3A4 INDUCERS/UBROGEPANT
- STRONG OR MODERATE CYP3A4 INDUCERS/VOXELOTOR
- STRONG OR MODERATE CYP3A4 INDUCERS/ZANUBRUTINIB
- P-GLYCOPROTEIN (P-GP) OR UGT INDUCERS/LETERMOVIR
- STRONG CYP3A4 INDUCERS/ISTRADEFYLLINE
- STRONG CYP3A4 OR P-GLYCOPROTEIN (P-GP) INDUCER/LEFAMULIN
- STRONG CYP3A4 INDUCERS/FEDRATINIB
- STRONG CYP3A4 INDUCERS/UPADACITINIB
- STRONG CYP3A4 INDUCERS/ENTRECTINIB
- STRONG AND MODERATE CYP3A4 INDUCERS/PRETOMANID
- STRONG CYP3A4 INDUCERS/PEXIDARTINIB
- SELECTED STRONG CYP3A4 INDUCERS; RIFABUTIN/BICTEGRAVIR
- STRONG CYP3A4 INDUCERS/TIVOZANIB
- STRONG CYP3A4 INDUCERS/ERDAFITINIB
- SELECTED MODERATE AND STRONG CYP3A4 INDUCERS/SIPONIMOD
- STRONG CYP3A4 INDUCERS; RIFABUTIN/LAROTRECTINIB
- STRONG CYP3A4 INDUCERS/GLASDEGIB
- STRONG CYP3A4 INDUCERS/DUVELISIB
- STRONG CYP3A4 INDUCERS/ERAVACYCLINE
- AGENTS THAT AFFECT CATECHOLAMINES/IOBENGUANE I 123
- AGENTS THAT AFFECT CATECHOLAMINES/IOBENGUANE I 131
- STRONG CYP3A4 INDUCERS/IVOSIDENIB
- STRONG CYP3A4 INDUCERS/ARIPIPRAZOLE LAUROXIL SUBMICRONIZED
- STRONG AND MODERATE CYP3A4 INDUCERS/ENCORAFENIB
- SELECTED BARBITURATES/SELECTED ANTICONVULSANTS
- SELECTED BARBITURATES/LAMOTRIGINE
- SELECTED BARBITURATES/ESLICARBAZEPINE
- SELECTED BARBITURATES/CARBAMAZEPINE
- STRONG CYP3A4 INDUCERS/MACIMORELIN
- STRONG CYP3A4 INDUCERS/ACALABRUTINIB
- STRONG CYP3A4 INDUCERS/ABEMACICLIB
- STRONG CYP3A4 INDUCERS/COPANLISIB
- STRONG AND MODERATE CYP3A4 INDUCERS/NERATINIB
- STRONG CYP3A4 INDUCERS; RIFABUTIN/BRIGATINIB
- STRONG CYP3A4 INDUCERS/MIDOSTAURIN
- STRONG CYP3A4 INDUCERS/NALDEMEDINE
- STRONG CYP3A4 INDUCERS/RIBOCICLIB
- STRONG CYP3A4 INDUCERS/VENETOCLAX
- STRONG CYP3A4 INDUCERS; RIFABUTIN/VEMURAFENIB
- STRONG CYP3A4 INDUCERS/TOFACITINIB
- SLT MODERATE AND STRONG CYP3A4 INDUCERS/IXAZOMIB
- STRONG CYP3A4 INDUCERS/OSIMERTINIB
- STRONG CYP3A4 INDUCERS/TRABECTEDIN
- STRONG CYP3A4 INDUCERS/FLIBANSERIN
- STRONG CYP3A4 INDUCERS/SELECTED ANTINEOPLASTICS
- STRONG CYP3A4 INDUCERS/NALOXEGOL
- STRONG CYP3A4 INDUCERS/ELIGLUSTAT
- STRONG CYP3A4 INDUCERS/RAMELTEON; SUVOREXANT; TASIMELTEON
- STRONG CYP3A4 INDUCERS/QUETIAPINE (> 150 MG)
- STRONG & MODERATE CYP3A4 INDUCERS/GUANFACINE
- STRONG OR MODERATE CYP3A4 INDUCERS/SIMEPREVIR
- SELECTED UGT1 & CYP3A4 INDUCERS/DOLUTEGRAVIR
- UGT INDUCERS/CANAGLIFLOZIN
- STRONG & MODERATE CYP3A4 INDUCERS/BEDAQUILINE
- STRONG CYP3A4 INDUCERS; RIFABUTIN/PONATINIB
- STRONG & MODERATE CYP2C8 OR CYP3A4 INDUCERS/ENZALUTAMIDE
- SELECTED STRONG CYP3A4 INDUCERS/BORTEZOMIB
- STRONG CYP3A4 INDUCERS/IVACAFTOR
- STRONG & MODERATE CYP3A4 INDUCERS/SELECTED ANTINEOPLASTICS
- P-GP & STRONG 3A4 INDUCERS;EFAVIRENZ;PB/APIXABAN;RIVAROXABAN
- STRONG CYP3A4 INDUCERS/TOREMIFENE
- STRONG P-GP OR CYP3A4 INDUCER/LINAGLIPTIN
- STRONG CYP3A4 INDUCERS/TICAGRELOR; VORAPAXAR
- STRONG CYP3A4 INDUCERS/APREMILAST; ROFLUMILAST
- CARBAMAZEPINE; PHENOBARBITAL; PHENYTOIN/IXABEPILONE
- STRONG CYP3A4 INDUCERS; RIFABUTIN/ROMIDEPSIN
- STRONG UGT INDUCERS/DEFERASIROX
- CARBAMAZEPINE; PHENOBARBITAL; PHENYTOIN/ULIPRISTAL
- CARBAMAZEPINE;PHENOBARBITAL;PHENYTOIN/AMIODARONE;DRONEDARONE
- STRONG CYP3A4 INDUCERS/TOLVAPTAN
- STRONG CYP3A4 INDUCERS/SELECTED IMMUNOSUPPRESSANTS
- SELECTED ANTICONVULSANTS/FESOTERODINE
- STRONG CYP3A4 INDUCERS/MARAVIROC
- SELECTED ANTICONVULSANTS/IRINOTECAN
- PHENOBARBITAL; PHENYTOIN; PRIMIDONE/DARUNAVIR
- SELECTED ANTICONVULSANTS/POSACONAZOLE
- STRONG 3A4 INDUCERS/SLT ANTINEOPLASTIC SYSTEMIC ENZYME INHIB
- STRONG CYP3A4 INDUCERS/IVABRADINE
- STRONG CYP3A4 INDUCERS/EXEMESTANE
- STRONG CYP3A4 INDUCERS/APREPITANT; NETUPITANT; ROLAPITANT
- SYMPATHOMIMETICS/SELECTED INHALATION ANESTHETIC AGENTS
- XANTHINE DERIVATIVES/ADENOSINE; HEXOBENDINE; REGADENOSON
- SYMPATHOMIMETICS (INDIRECT ACTING)/GUANETHIDINE
- BARBITURATES/METHOXYFLURANE
- PHENYTOIN; PHENOBARBITAL; RIFAMPIN/CLOZAPINE
- SYMPATHOMIMETICS/ERGOT ALKALOIDS
- STR 3A4 INDUCER;SLT BARBITURATES,HYDANTOIN/SLT ANTIMALARIALS
- BARBITURATES/SELECTED ANTICOAGULANTS (VIT K ANTAGONISTS)
Moderate Interactions
These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
- SYMPATHOMIMETICS/URINARY ALKALINIZERS
- SELECTED XANTHINE DERIVATIVES/SELECTED MACROLIDE ANTIBIOTICS
- SYMPATHOMIMETICS/RAUWOLFIA ALKALOIDS
- THEOPHYLLINE/ZILEUTON
- THEOPHYLLINE DERIVATIVES/LITHIUM
- SYMPATHOMIMETICS (DIRECT, MIXED-ACTING)/METHYLDOPA
- THEOPHYLLINES/THIABENDAZOLE
- SELECTED ANTICONVULSANTS/ESTROGENS
- XANTHINE DERIVATIVES/CHARCOAL
- SELECTED XANTHINE DERIVATIVES/FLUVOXAMINE
- SELECTED THEOPHYLLINE DERIVATIVES/MORICIZINE
- THEOPHYLLINE/FEBUXOSTAT
- BARBITURATES/PHENOTHIAZINES
- THEOPHYLLINE/MARIJUANA SMOKE
- THEOPHYLLINE DERIVATIVES/SELECTED CYP1A2 INHIBITORS
- SELECTED CYP1A2 SUBSTRATES/OBETICHOLIC ACID
- SELECTED CYP1A2 OR CYP2D6 SUBSTRATES/GIVOSIRAN
- SELECTED CYP1A2 SUBSTRATES/OSILODROSTAT
- BARBITURATES/HALOPERIDOL
- THEOPHYLLINE DERIVATIVES/FAVIPIRAVIR
- BETA-AGONISTS; ANTICHOLINERGICS; THEOPHYLLINE/METHACHOLINE
- STRONG UGT INDUCERS; NEVIRAPINE/ARTESUNATE
- STRONG CYP3A4 INDUCERS/CANNABIDIOL; TETRAHYDROCANNABINOL
- STRONG CYP3A4 INDUCERS/PITOLISANT
- BARBITURATES/RIFAMPIN
- STRONG CYP3A4 INDUCERS/FOSTAMATINIB
- STRONG AND MODERATE CYP3A4 INDUCERS/PERAMPANEL
- STRONG CYP3A4 INDUCERS/VALBENAZINE
- PHENOBARBITAL; PRIMIDONE/SELECTED BENZODIAZEPINES
- PHENOBARBITAL; PHENYTOIN/CLARITHROMYCIN; ERYTHROMYCIN
- STRONG AND MODERATE CYP3A4 INDUCERS/PIMAVANSERIN
- SELECTED P-GP INDUCERS; PHENOBARBITAL/TENOFOVIR ALAFENAMIDE
- PHENOBARBITAL; PRIMIDONE/SELECTED OPIOIDS
- STRONG CYP3A4 INDUCERS/VILAZODONE
- P-GLYCOPROTEIN (P-GP) INDUCERS; PHENOBARBITAL/AFATINIB
- STRONG CYP3A4 INDUCERS/BOSENTAN; MACITENTAN
- STRONG CYP3A4 INDUCERS/SELECT SEDATIVE HYPNOTICS; BUSPIRONE
- THEOPHYLLINE/BUPROPION
- PHENOBARBITAL; PHENYTOIN; PRIMIDONE/TIRILAZAD
- STRONG CYP3A4 INDUCERS/SELECTED ANTIPSYCHOTICS
- SELECTED ANTICONVULSANTS/FELODIPINE
- BARBITURATES/METRONIDAZOLE
- CYP3A4 INDUCERS/DOXYCYCLINE
- XANTHINE DERIVATIVES/CONTRACEPTIVES
- SELECTED CYP3A4 INDUCERS/CORTICOSTEROIDS
- BARBITURATES/SELECTED BETA-BLOCKERS
- THEOPHYLLINES/SELECTED BETA-BLOCKERS
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