What should I Know Regarding Pregnancy, Nursing and Administering Prevpac Oral to Children or the Elderly?
If you are pregnant Not Recommended: Not Recommended: Not Recommended:
If you are nursing Precaution: INSUFFICIENT HUMAN DATA AVAIL; LOW MW, EXCRETION POSSIBLE Precaution: LOW AMOUNT EXCRETED UNLIKELY TO AFFECT NURSING INFANT;MONITOR FOR DIARRHEA Precaution: MAY CAUSE SENSITIZATION, DIARRHEA OR RASH IN NURSING INFANT.
If you are an adult over 60 management or monitoring precaution: General-Prolonged use may decrease absorption of Vitamin B-12. Avoid for >8 weeks duration unless for high risk patients (eg. oral corticosteroids or chronic NSAID use), erosive esophagitis, Barrett's esophagitis, pathologic hypersecretory condition, or demonstrated need for maintenance treatment. Musculoskeletal-Increased risk of fracture with high dose or prolonged use of greater than 1 year. Gastrointestinal-Long term use may be associated with C. difficile diarrhea. management or monitoring precaution: Renal-May need to adjust dosage for renal impairment. management or monitoring precaution: Renal-May require dosage adjustment with severe renal impairment to minimize risk of QT-prolongation. Cardiovascular-Contraindicated in patients with pre-existing QT prolongation. Elderly may be more susceptible to Torsades de Pointes.
Pediatric use Severe Precaution: Rare reports of tooth discoloration or staining; may be reduced with cleaning or brushing. Severe Precaution: Adhere to recommended dose and duration of therapy. Unknown safety and efficacy for long term treatment. Severe Precaution: Risk of heart valve thickening and bone changes based on animal studies. Efficacy not established in pediatric trials for symptomatic GERD age <1 year. Severe Precaution: Safety and efficacy not established age < 6 months.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.