Does Cyclosporine Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED CYP3A4 SUBSTRATES/MIFEPRISTONE
  • SELECTED NEPHROTOXIC AGENTS/BACITRACIN
  • SLT IMMUNOSUPPRESSANTS;TEMSIROLIMUS/NIRMATRELVIR-RITONAVIR
  • WEAK CYP3A4 INHIBITORS/LEMBOREXANT (> 5 MG)
  • CYCLOSPORINE/LETERMOVIR (> 240 MG)
  • CYCLOSPORINE/LERCANIDIPINE
  • STRONG OATP1B1 INHIBITORS/ELAGOLIX
  • WEAK CYP3A4 INHIBITORS/LOMITAPIDE (>30 MG)
  • OATP1B1-3 INHIBITORS/ELBASVIR-GRAZOPREVIR
  • SELECTED IMMUNOSUPPRESSANTS/TALIMOGENE LAHERPAREPVEC
  • CYCLOSPORINE/ATORVASTATIN (> 10 MG)
  • SELECTED IMMUNOSUPPRESSANTS/TOFACITINIB
  • CYCLOSPORINE/AMBRISENTAN (> 5 MG)
  • CYCLOSPORINE/FLUV (>20BID); PIT; PRAV (>20); ROS (>5); SIMVA
  • CALCINEURIN INHIBITORS/MIFAMURTIDE
  • STRONG CYP3A4 INHIBITORS; ATAZANAVIR; DARUNAVIR/DRONEDARONE
  • CYCLOSPORINE/ALISKIREN
  • SELECTED IMMUNOSUPPRESSIVE AGENTS/LIVE VACCINES; LIVE BCG
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/EFALIZUMAB; NATALIZUMAB
  • CYCLOSPORINE/TACROLIMUS
  • CYCLOSPORINE/BOSENTAN; SITAXSENTAN
  • SELECTED AGENTS/MIBEFRADIL
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED IMMUNOSUPPRESSANTS/SELECTED AZOLE ANTIFUNGAL AGENTS
  • CYCLOSPORINE/AMPHOTERICIN B
  • CYCLOSPORINE/SELECTED ANDROGENS
  • SELECTED IMMUNOSUPPRESSANTS;TEMSIROLIMUS/SELECTED MACROLIDES
  • CYCLOSPORINE; EVEROLIMUS; SIROLIMUS; TACROLIMUS/NSAIDS
  • CYCLOSPORINE/ORLISTAT
  • CYCLOSPORINE/QUINUPRISTIN-DALFOPRISTIN
  • CYCLOSPORINE;TACROLIMUS/POTASSIUM-SPARING DIURETICS
  • SLT IMMUNOSUPPRESSANTS;TEMSIROLIMUS/PROTEASE INH;COBICISTAT
  • SELECTED IMMUNOSUPPRESSANTS/STRONG CYP3A4 INDUCERS
  • CYCLOSPORINE/METHOTREXATE
  • CYCLOSPORINE/COAL TAR
  • SELECTED CYP3A4 SUBSTRATES/CERITINIB
  • SENSITIVE CYP3A4; CYP2C9; CYP2C19 SUBSTRATES/ENZALUTAMIDE
  • CYCLOSPORINE/EVEROLIMUS
  • SELECTED IMMUNOSUPPRESSANTS/POSACONAZOLE; VORICONAZOLE
  • SELECTED NEPHROTOXIC AGENTS/FOSCARNET
  • SELECTED IMMUNOSUPPRESSANTS; TEMSIROLIMUS/SAQUINAVIR
  • CYCLOSPORINE;SIROLIMUS;TEMSIROLIMUS/RIBOCICLIB
  • SELECTED IMMUNOSUPPRESSANTS/CONIVAPTAN
  • SELECTED IMMUNOSUPPRESSANTS/IDELALISIB
  • SELECTED NEPHROTOXIC AGENTS/INOTERSEN
  • SELECTED IMMUNOSUPPRESSANTS/CHLORAMPHENICOL
  • CYCLOSPORINE/OMBITASVIR-PARITAPREVIR-RITONAVIR
  • SELECTED SENSITIVE CYP3A4 SUBSTRATES/VOXELOTOR
  • SELECTED CYP3A4 SUBSTRATES/CRIZOTINIB
  • SELECTED SENSITIVE CYP3A4 SUBSTRATES/TUCATINIB
  • SELECTED IMMUNOSUPPRESSANTS/LEVOKETOCONAZOLE
  • SELECTED CYP3A4 SUBSTRATES/MITAPIVAT
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/BILASTINE
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/DOXORUBICIN
  • SELECTED INHIBITORS OF BCRP WITH MYELOSUPPRESSION/CLADRIBINE
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/SIPONIMOD
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/OZANIMOD
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/FINGOLIMOD
  • P-GP INHIBITORS/RIMEGEPANT
  • MYELOSUPPRESSIVES; IMMUNOMODULATORS/SODIUM IODIDE I 131
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/FILGOTINIB
  • OATP1B1-3 INHIBITORS/BRINCIDOFOVIR
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/PONESIMOD
  • SELECTED IMMUNOSUPPRESSANTS/LEFLUNOMIDE; TERIFLUNOMIDE
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/RELUGOLIX
  • WEAK CYP3A4 INHIBITORS/LONAFARNIB
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/BARICITINIB
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/INEBILIZUMAB
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/UPADACITINIB
  • WEAK CYP3A4 INHIBITORS/ELIGLUSTAT
  • CYCLOSPORINE/OBETICHOLIC ACID
  • CYCLOSPORINE/GLECAPREVIR-PIBRENTASVIR
  • SELECTED OATP INHIBITORS/VOXILAPREVIR
  • SELECTED INHIBITORS OF P-GP OR BCRP/PAZOPANIB
  • IMMUNOSUPPRES;IMMUNOMODUL/SELECTED MULTIPLE SCLEROSIS AGENTS
  • OATP1B1 INHIBITORS/ELUXADOLINE
  • SELECTED P-GP INHIBITORS/EDOXABAN (> 30 MG)
  • BILE SALT EFFLUX PUMP (BSEP) INHIBITORS/CHOLIC ACID
  • WEAK CYP3A4 INHIBITORS/LOMITAPIDE (<=30MG)
  • SELECTED CYP3A4 INHIBITOR/TOLTERODINE (>1 MG IR OR >2 MG ER)
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/TOPOTECAN
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/DABIGATRAN
  • SELECTED NEPHROTOXIC AGENTS/COLISTIMETHATE
  • CYCLOSPORINE/COLCHICINE
  • CYCLOSPORINE/CASPOFUNGIN
  • CYCLOSPORINE/ATORVASTATIN (<= 10 MG); LOVASTATIN
  • CYCLOSPORINE/DIGOXIN
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • CYCLOSPORINE; SIROLIMUS/METOCLOPRAMIDE
  • CYCLOSPORINE/CALCIUM CHANNEL BLOCKERS
  • CYCLOSPORINE/AMIODARONE
  • CYCLOSPORINE/OCTREOTIDE
  • CYCLOSPORINE/SELECTED QUINOLONES
  • CYCLOSPORINE/NEFAZODONE
  • CYCLOSPORINE/COLESEVELAM
  • SELECTED NEPHROTOXIC AGENTS/IMMUNE GLOBULIN IV (IGIV)
  • CYCLOSPORINE/SELECTED FIBRATES
  • CYCLOSPORINE/TIGECYCLINE
  • SELECTED P-GLYCOPROTEIN (P-GP) SUBSTRATES/ABROCITINIB
  • SELECTED IMMUNOSUPPRESSANTS/MARIBAVIR
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/SARILUMAB; TOCILIZUMAB
  • OATP1B1-3 INHIBITORS/ATOGEPANT
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/COVID-19 VACCINES
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/USTEKINUMAB
  • WEAK CYP3A4 INHIBITORS/UBROGEPANT
  • WEAK CYP3A4 INHIBITORS/LEMBOREXANT (<= 5 MG)
  • SELECTED P-GP INHIBITORS/EDOXABAN (<= 30 MG)
  • CYCLOSPORINE/LETERMOVIR (<= 240 MG)
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/BETRIXABAN
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/AFATINIB
  • SELECTED P-GP AND WEAK CYP3A4 INHIBITORS/RIVAROXABAN
  • CYCLOSPORINE/AMBRISENTAN (<=5 MG)
  • CYCLOSPORINE/REPAGLINIDE
  • SELECTED NEPHROTOXIC AGENTS/TENOFOVIR
  • CYCLOSPORINE/EZETIMIBE
  • CYCLOSPORINE/FLUVA(<=20MG BID);PRAVA(<=20MG);ROSUVA(<=5MG)
  • SELECTED CYP3A4 INHIBITORS/TOLTERODINE (<=1 MG OR <=2 MG ER)
  • CYCLOSPORINE/SIROLIMUS; TEMSIROLIMUS
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/ETOPOSIDE
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    Drug Survey

    Are you currently using Cyclosporine?

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.