Arbutamine/Atropine Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

These medications have the same effect on your heart and may increase your heart rate when taken together.

What might happen:

When these two medicines are taken together, your doctor may have a hard time determining your dose of arbutamine.

What you should do about this interaction:

Contact your healthcare professionals (e.g. doctor or pharmacist) as soon as possible about taking these two medicines together.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Genesa (arbutamine) US prescribing information. Gensia Automedics August, 1997.
  • 2.Shehata AR, Ahlberg AW, Gillam LD, Mascitelli VA, Piriz JM, Fleming RA, Chen C, Waters DD, Heller GV. Direct comparison of arbutamine and dobutamine stress testing with myocardial perfusion imaging and echocardiography in patients with coronary artery disease. Am J Cardiol 1997 Sep 15;80(6):716-20.
  • 3.Wilson ME, Lee GK, Chandra A, Kane GC. Central anticholinergic syndrome following dobutamine-atropine stress echocardiography. Echocardiography 2011 Nov;28(10):E205-6.
  • 4.Ketteler T, Krahwinkel W, Wolfertz J, Godke J, Hoffmeister T, Scheuble L, Gulker H. Arbutamine stress echocardiography. Eur Heart J 1997 Jun;18 Suppl D:D24-30.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.