Who should not take IMIPRAMINE HCL?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • overactive thyroid gland
  • schizophrenia
  • manic-depression
  • suicidal thoughts
  • alcoholism
  • alcohol intoxication
  • serotonin syndrome, a type of disorder with high serotonin levels
  • increased pressure in the eye
  • closed angle glaucoma
  • heart attack within the last 30 days
  • abnormal heart rhythm
  • chronic heart failure
  • a stroke
  • orthostatic hypotension, a form of low blood pressure
  • paralysis of the intestines
  • blocked bowels with decreased peristaltic movement
  • liver problems
  • decreased kidney function
  • enlarged prostate
  • recent operation
  • seizures
  • an inability to completely empty the bladder
  • pregnancy
  • chronic idiopathic constipation
  • CYP2D6 poor metabolizer
  • risk of angle-closure glaucoma due to narrow angle of anterior chamber of eye

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.