Bictegravir/Aluminum, Calcium & Magnesium Antacids; Buffered Medications; Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Antacids that contain aluminum, calcium and/or magnesium, buffered medications, or sucralfate may bind to bictegravir in your GI tract.

What might happen:

Your body may not absorb the full dose of your bictegravir and it may not work as well.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to run some blood tests to check how your medicine is working. Bictegravir should be taken on an empty stomach at least 2 hours before aluminum, calcium and/or magnesium containing antacids, buffered medications, or sucralfate. Avoid taking bictegravir at the same time or 2 hours after aluminum, calcium and/or magnesium containing antacids, buffered medications, or sucralfate.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Biktarvy (bictegravir, emtricitabine, tenofovir alafenamide) US prescribing information. Gilead Sciences, Inc. February, 2018..

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.