What should I Know Regarding Pregnancy, Nursing and Administering Zocor to Children or the Elderly?

If you are pregnant

  • Not Recommended:
  • If you are nursing

  • Precaution: CONTRAINDICATED PER MANUFACTURER; OTHER HMG REDUCTASE INHIB EXCRETED IN MILK
  • If you are an adult over 60

  • management or monitoring precaution: Musculoskeletal-Higher incidence of myopathy or rhabdomyolysis with age over 65 particularly with renal disease. Plasma levels in the elderly are 45% higher. FDA MedWatch(06/09/2011) recommends against the use of the 80mg dose for new drug starts regardless of age, and only allows for use in those patients stabilized on 80mg with no evidence for myopathy. Do not titrate beyond 40mg/day to achieve LDL-C goal. Alternative agents should be considered. Hepatic-Monitor LFTs; liver dysfunction.
  • Pediatric use

  • Severe Precaution: Safety and effectiveness not established for pediatric patients < 10 years; manufacturer did not study use in girls pre-menarche.
  • Severe Precaution: Manufacturer recommends post-menarche females be counseled on appropriate contraception.
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    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.