SULFASALAZINE Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • increased sensitivity of the skin to the sun
  • inflammation of the skin due to an allergy
  • itching
  • a fever as a result of taking the medication
  • a skin rash

If experienced, these tend to have a Less Severe expression i

  • indigestion
  • low sperm count
  • skin discoloration
  • dizziness
  • decreased appetite
  • nausea
  • vomiting
  • diarrhea
  • abnormal color of urine
  • intense abdominal pain

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • a type of blood disorder where the red blood cells burst called hemolytic anemia
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • a blood disorder
  • ulcerative colitis, an inflammatory condition of the intestines
  • inflammation of the liver called hepatitis
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a bluish discoloration of the skin

If experienced, these tend to have a Less Severe expression i

    Sorry, we have no data available. Please contact your doctor or pharmacist.

    RARE side effects

    If experienced, these tend to have a Severe expression i

    • glucose-6-phosphate dehydrogenase (G6PD) deficiency anemia
    • hemolytic uremic syndrome, a condition that affects the kidney and the blood
    • low blood counts due to bone marrow failure
    • a decrease in the blood clotting protein prothrombin
    • increased eosinophils in the blood
    • methemoglobinemia, a type of blood disorder
    • inflammation of the spinal cord
    • Guillain-Barre syndrome
    • hearing loss
    • inflammation of the middle tissue heart muscle
    • pneumonia
    • a type of inflammation of the lung called interstitial pneumonitis
    • inflammation of the alveoli of the lungs
    • pneumonia with high amount of eosinophil white blood cells
    • stomatitis, a condition with painful swelling and sores inside the mouth
    • inflammation of the small and large intestine
    • liver tissue death
    • liver damage
    • liver failure
    • a blockage of the bile duct that resulting in high bilirubin levels
    • blockage of normal bile flow
    • nephrotic syndrome, a type of kidney disorder
    • kidney inflammation
    • kidney stones
    • decreased kidney function
    • erythema multiforme, a type of allergic skin reaction
    • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
    • skin rash with sloughing
    • hives
    • a condition with muscle tissue breakdown called rhabdomyolysis
    • myelodysplastic syndrome, a bone marrow disorder
    • hallucinations
    • high amount of bilirubin in the blood
    • abnormal liver function tests
    • a significant type of allergic reaction called anaphylaxis
    • a type of allergic reaction called angioedema
    • a serum sickness reaction
    • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
    • cessation of urine production
    • pancreatitis
    • neutropenic colitis
    • sepsis
    • a high alanine transaminase level
    • a high aspartate transaminase level

    If experienced, these tend to have a Less Severe expression i

    • a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
    • fluid accumulation around the eye
    • urinary tract infection
    • drowsiness
    • sensation of spinning or whirling
    • difficulty sleeping
    • loss of muscle coordination
    • loss of skin color
    • pain in the oropharynx

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.