OXALIPLATIN Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • anemia
  • decreased blood platelets
  • low levels of white blood cells
  • obstruction of a blood vessel by a blood clot
  • joint pain
  • visible water retention
  • erythrodysesthesia or tingling, pain, redness, and edema in the hands and feet
  • trouble breathing
  • cough
  • chest pain
  • abnormal liver function tests
  • reactions at the site of the injection

If experienced, these tend to have a Less Severe expression i

  • throat irritation
  • a stuffy and runny nose
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • indigestion
  • constipation
  • hair loss
  • backache
  • muscle pain
  • dizziness
  • difficulty sleeping
  • fever
  • low energy
  • chills
  • taste impairment
  • decreased appetite
  • headache
  • nausea
  • vomiting
  • diarrhea
  • high blood sugar
  • a feeling of pins and needles on skin
  • abnormal sensations of the skin
  • intense abdominal pain

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • low amount of albumin proteins in the blood
  • low amount of calcium in the blood
  • low amount of sodium in the blood
  • dehydration
  • low amount of potassium in the blood
  • depression
  • bronchospasm
  • a hypersensitivity reaction to a drug

If experienced, these tend to have a Less Severe expression i

  • excessive watery eyes
  • dry mouth
  • gastroesophageal reflux disease
  • itching
  • dry skin
  • hives
  • excessive sweating
  • a skin rash
  • fluid retention in the legs, feet, arms or hands
  • temporary redness of face and neck
  • nosebleed
  • hiccups
  • gas
  • difficult or painful urination
  • an increased need to urinate often
  • anxious feelings

RARE side effects

If experienced, these tend to have a Severe expression i

  • diarrhea from an infection with Clostridium difficile bacteria
  • excess body acid
  • hemolytic uremic syndrome, a condition that affects the kidney and the blood
  • low levels of granulocytes, a type of white blood cell
  • low levels of a type of white blood cell called neutrophils
  • changes in the visual field
  • vision loss
  • a decrease in sharpness of vision called reduced visual acuity
  • sudden blindness and pain upon moving the eye
  • hearing loss
  • torsades de pointes, a type of abnormal heart rhythm
  • slow heartbeat
  • prolonged QT interval on EKG
  • ventricular arrhythmias, a type of abnormal heart rhythm
  • hepatic veno-occlusive disease, a type of liver disease
  • low blood pressure
  • bleeding
  • a spasm of the larynx
  • a type of inflammation of the lung called interstitial pneumonitis
  • a condition where there is formation of fibrous tissue in the lung called pulmonary fibrosis
  • blocked bowels with decreased peristaltic movement
  • blockage of the stomach or intestine
  • microscopic blood-filled cavities in the liver
  • acute inflammation of the pancreas
  • a type of kidney inflammation called interstitial nephritis
  • acute kidney failure
  • renal tubular necrosis, a kidney disorder
  • decreased kidney function
  • a condition with muscle tissue breakdown called rhabdomyolysis
  • muscle weakness
  • seizures
  • muscle twitching
  • a type of speech disorder called dysarthria
  • a significant drop in blood pressure due to bacterial infection
  • excessive diarrhea
  • weak reflexes
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • Lhermitte's sign, a sensation of an electric shock passing down the back of the neck and spine
  • lung tissue problem
  • a type of brain disorder called posterior reversible encephalopathy syndrome
  • cranial nerve palsy
  • peripheral sensory nerve disorder

If experienced, these tend to have a Less Severe expression i

  • numbness

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.