This medication is used to treat and prevent wheezing and trouble breathing caused by ongoing lung disease (e.g., asthma, emphysema, chronic bronchitis). Aminophylline belongs to a class of drugs known as xanthines. It works in the airways by relaxing muscles, opening air passages to improve breathing, and decreasing the lungs' response to irritants. Controlling symptoms of breathing problems can decrease time lost from work or school.
This medication does not work right away and should not be used for sudden attacks of breathing trouble. Your doctor should prescribe a quick-relief medicine/inhaler (e.g., albuterol) for sudden attacks of shortness of breath/asthma while you are on this medication. You should always have a quick-relief inhaler with you. Consult your doctor or pharmacist for more details.
Do not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
Certain diets (such as high protein/low carbohydrate or high carbohydrate/low protein) may change the effect of aminophylline. Tell your doctor if you have any major changes in your diet. Your doctor may need to adjust your dose.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.
Inform your doctor if your condition persists or worsens.
Stomach pain/cramping, nausea, vomiting, diarrhea, loss of appetite, headache, trouble sleeping, irritability, restlessness, nervousness, shaking (tremors), flushing, and increased urination may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, red/scaly skin, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Before using aminophylline, tell your doctor or pharmacist if you are allergic to it; or to theophylline, theobromine, caffeine, or ethylenediamine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain breathing disorder (cystic fibrosis), diabetes, glaucoma, heart problems (e.g., congestive heart failure, irregular heartbeat), high blood pressure, kidney disease, liver disease (e.g., cirrhosis), seizures, stomach/intestinal ulcer, thyroid disease.
If you develop a fever/flu-like symptoms while taking this medication, tell your doctor promptly. The dose of your medicine may need to be adjusted.
Before having surgery, tell your doctor or dentist that you are taking this medication.
Caution is advised when using this drug in the elderly because they may be more sensitive to its effects. Careful monitoring of side effects and drug blood levels is recommended.
Caution is advised when using this drug in children because they may be more sensitive to its effects. Careful monitoring of side effects, drug blood levels, and dose adjustment is recommended.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Changes in your body during the last 3 months of pregnancy may affect the amount of this drug in your blood. Your doctor should carefully monitor the amount of drug in your blood, as well as any side effects, so that your dose may be changed if needed.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
A product that may interact with this drug is: riociguat.
Other medications can affect the removal of aminophylline from your body, which may affect how aminophylline works. Examples include cimetidine, disulfiram, fluvoxamine, interferon, mexiletine, propranolol, rifampin, drugs used to treat seizures (such as carbamazepine, phenytoin), St. John's wort, ticlopidine, among others.
Caffeine and alcohol can increase the side effects of this medication. Avoid drinking large amounts of beverages containing alcohol or caffeine (such as coffee, tea, colas), eating large amounts of chocolate, or taking nonprescription products that contain caffeine.
Aminophylline is very similar to theophylline. Do not take medications containing theophylline while using aminophylline.
This medication may interfere with certain lab tests (such as blood sugar, cholesterol, uric acid, dipyridamole-thallium imaging tests), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: agitation, nausea, frequent vomiting, trouble sleeping, unusual thirst, fever, ringing in the ears, seeing flashes of light, fast/irregular heartbeat, seizures, confusion, chest pain.
Laboratory and/or medical tests (e.g., theophylline blood levels) should be performed periodically to monitor your progress or check for side effects. It is important that you do not miss your medication or take extra doses for 2-3 days before your theophylline blood levels are checked. Consult your doctor for more details.
If you miss a dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.Information last revised March 2017. Copyright(c) 2017 First Databank, Inc.
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