Hormonal Contraceptives/Artemether Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

When these two medicines are taken together, your body may process your birth control pill faster.

What might happen:

The effects of your birth control pills may decrease and cause breakthrough bleeding, spotting, or pregnancy. The effects of the interaction may last for several weeks after you stop taking artemether.

What you should do about this interaction:

Talk to your healthcare professional (e.g. doctor, pharmacist) as soon as possible about using a different form of birth control while you are taking artemether and for 28 days after stopping artemether. Contact your doctor if you experience breakthrough bleeding, spotting, or pregnancy.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Coartem (artemether/lumefantrine) US prescribing information. Novartis Pharmaceuticals Corporation March, 2015.
  • 2.Faculty of Sexual and Reproductive Healthcare Clinical Effectiveness Unit. Clinical guidance drug interactions with hormonal contraception. January, 2011.